Resource Library
Explore our comprehensive library of courses, videos, podcasts, articles, books, news, and events.
Search Resources
Efficient Generation of Pancreatic Progenitor Cells from Induced Pluripotent Stem Cells Derived from a Non-Invasive and Accessible Tissue Source—The Plucked Hair Follicle
Dr. Seeds reviews how cryopreserved hair follicles may offer a simpler, non-invasive source for future stem cell research and pancreatic cell development. (Article Link)
Kelli Musa returns to unpack her Self-Led Woman framework, mapping how hormonal, metabolic, neurological, and cellular systems collide during perimenopause and menopause. Dr. Seeds ties the discussion to mitochondrial biogenesis and cellular decision-making, while the group explores GLP-1s, BPC-157, and TB-500 for weight, inflammation, and tissue repair.
Dr. Seeds’ Office Hours – Episode 095
1. Sjögren’s, POTS, Mold, Biofilms & Lumbrokinase (0:45)
2. PMDD, Allopregnanolone & Mitochondrial Efficiency (7:28)
3. Retatrutide, Glucagon & Metabolic Flexibility (20:01)
Functional wellness practitioner Kelli Musa joins the show to challenge how mainstream medicine handles women's hormonal health. The conversation revisits the misread 2002 hormone study, the difference between normal and optimal hormone levels, and how cortisol, estrogen, and progesterone work as an interconnected system through perimenopause and beyond.
Cellular Optimization for EDS Surgical Support
Dr. Seeds reviews peptide and supplemental considerations for cellular optimization in an EDS patient preparing for orthopedic surgery. (Question Link)
Recorded live at Peptide World Congress 2026, Dr. William Seeds makes the case against symptom-based medicine and walks through how cells actually make decisions: sensing redox balance, allocating energy through AMPK and mTOR, activating NRF2 antioxidant defenses, and protecting mitochondrial DNA. A phenotype-guided framework for cellular optimization.
The Phosphatidylcholine Pathway
Dr. Seeds expands on Journal Club Episode 92 to explore the role of phosphatidylcholine in lipid metabolism, methylation, and mitochondrial integrity during aging. He also highlights how estrogen loss may impact this pathway, especially in pre- and post-menopausal women.
Dr. Seeds reframes modern care around phenotyping rather than treating symptoms or diagnoses, explaining why peptides work as signaling molecules that help cells make better decisions. Matt and Maddie also preview the Peptide World Congress and the launch of a graduate-level cellular medicine course.
Aging-Associated Decline of Phosphatidylcholine Synthesis is a Malleable Trigger of Natural Mitochondrial Aging
Dr. Seeds explores how age-related decline in phosphatidylcholine synthesis may contribute to mitochondrial aging and why that matters in Cellular Medicine. This discussion connects membrane integrity, mitochondrial function, methylation, and metabolic resilience, while highlighting how this pathway may be more modifiable than we once thought.
The FDA has announced safety and efficacy reviews of roughly a dozen compounded peptides, including BPC-157, TB-500, DSIP and Melanotan 2, moving several off the restricted category 2 list. Dr. Seeds unpacks the PCAC review process, API manufacturing standards, and why preclinical mechanisms still need human clinical evidence.
1. Managing shingles outbreaks in GLP-1 patient through peptides (0:40)
2. Peptide strategies in suspected ALS (15:56)
3. Improving durability in dementia treatment (25:08)
Dr. Seeds separates stretching fact from gym-floor fallacy, explaining why static holds before training can backfire while dynamic mobility work prepares the body. He digs into the molecular payoff of stretching done correctly, from inhibiting myostatin and boosting follistatin to adding sarcomeres in series for better contraction velocity.
In this bonus episode from the MM15 Virtual Summit, Dr. Seeds addresses an important question around the use of GLP-1s for metabolic balancing in patients who do not need to lose weight. He shares his perspective on what may be considered microdosing, along with the clinical thought process he uses when determining appropriate dosing in these more nuanced cases.
Additional questions from the MM15 Virtual Summit can be found in our accompanying article here: [insert article link]
Access the full MM15 Course here: Mastermind 15 on Aesthetics