Mastermind 12: Exercise Metabolism & Performance

Exercise is not just about improving physical performance—it’s a powerful therapeutic tool that optimizes cellular health, metabolic flexibility, and systemic resilience. When strategically combined with peptides, small molecules, repurposed drugs, and targeted supplements, it becomes an even more potent intervention to prevent and manage chronic diseases, enhance healthspan, and mitigate age-related decline.

At Cellular Medicine Mastermind 12: Exercise Metabolism & Performance, you’ll come away confident in your ability to optimize patient healthspan, disease management, and performance by incorporating exercise protocols alongside an array of covered therapeutics

3-Days of In-Depth Lectures by Dr. Seeds

Dr. William Seeds, MD

Dr. Seeds, the Founder and Academic Chairman of the SSRP, has been honored at the NFL Hall of Fame for his medical expertise in treating professional athletes, and served as a Professional Medical Consultant for the NHL, MLB, NBA, and NBC’s Dancing With The Stars. He is a medical researcher, continuing to write and publish on the NIH and other medical journals, and is the author of Peptide Protocols Vol.1, the world’s first handbook about peptides written for practitioners.

Mastermind 12 Schedule Preview

A few of the key topics you can expect at Mastermind 12:

Exercise Performance and Cellular Health
Exercise’s Impact on Metabolism and Insulin Sensitivity
Redox: The Core of Exercise Adaptation and Healthspan
Exercise and the Immune System
Exercise and Mitochondrial Health
Enhancing Muscle Recovery/Repair: Exercise As We Age
Peptides and Small Molecules for Performance

Check out the full agenda below for all planned topics. (Sessions and times are subject to change)

December 5th: Day 1

1:00 pm - 2:40 pm: Lecture #1

Introduction: Exercise Performance and Cellular Health
Overview of the connection between exercise and cellular function.
Importance of cellular redox, mitochondrial health, and disease impact.
Setting the stage: Exercise as a therapeutic intervention beyond physical fitness.
Enhancing Muscle Recovery and Repair: Exercise as We Age
Cellular stress responses and their role in muscle repair.
Mechanisms of muscle and nerve recovery with aging.
How aging impacts cellular repair processes.
Role of exercise in preserving muscle and nerve function.

2:55 pm - 4:35 pm: Lecture #2

Cellular Redox: The Core of Exercise Adaptation and Healthspan
Basics of cellular redox: ROS and reactive nitrogen species.
Antioxidants’ role in regulating oxidative stress.
Impact of redox signaling on muscle and nerve function.
Hormetic response of exercise: balancing oxidative stress for adaptation.
Integrating Peptides and Small Molecules for Redox Modulation and Recovery
Key peptides: BPC-157, TB-4, and others in their role in enhancing recovery.
Small molecules: Nrf2 activators, CoQ10, and NAD+ in cellular redox.
Therapeutic strategies for optimizing redox balance and cellular health.

4:50 pm - 6:30 pm: Lecture #3

Exercise and Mitochondrial Health: From ATP to Autophagy
Role of mitochondria in exercise-induced adaptations.
Mitochondrial dynamics: fission, fusion, and mitophagy.
How exercise drives mitochondrial biogenesis.
Autophagy and its role in maintaining mitochondrial health.
Practical strategies to enhance mitochondrial function through exercise, peptides, and small molecules.

December 6th: Day 2

1:00 pm - 2:40 pm: Lecture #4

Understanding Exercise’s Impact on Metabolism and Insulin Sensitivity
Mechanisms of exercise-induced glucose uptake.
Improving insulin sensitivity through muscle contraction.
Exercise as a tool for restoring metabolic flexibility.
Integrating Peptides, Repurposed Drugs, and Supplements for Metabolic Health
Peptides: GLP-1 agonists, GHRH/GHRP’s ,MOTS-c, SS-31 and their role in enhancing insulin sensitivity.
Repurposed drugs: Metformin?
Supplements: Plasmologens, Omega Fatty acids , Petadecanoic Acid, Alpha-lipoic acid, magnesium, and mitochondrial enhancers
Practical application in clinical settings.

2:55 pm - 4:35 pm: Lecture #5

The Role of the Autonomic Nervous System in Exercise Recovery and Performance
Sympathetic vs. parasympathetic regulation.
Heart rate variability (HRV) as a biomarker of autonomic balance.
Impact of stress on autonomic function and exercise recovery.
Strategies to optimize autonomic function through exercise.
Exercise and the Immune System: Myokines, Inflammation, and Immunity
Key myokines: IL-6, irisin, and their role in systemic inflammation.
Exercise-induced modulation of immune function.
Balancing inflammation: anti-inflammatory vs. pro-inflammatory exercise adaptations.
Clinical strategies for leveraging exercise in immune modulation.

4:50 pm - 6:30 pm: Lecture #6

Optimizing the Immune Response with Peptides, Supplements, and Small Molecules
Immune-supporting peptides: Thymosin alpha-1 and TB-4
Supplement strategies: Zinc, vitamin D, omega-3s,plasmologens, Pentadecanoic Acid, polyphenols
Small molecules: PPS54 and their impact on immune regulation
Integrating these approaches to enhance exercise recovery and systemic immunity

December 7th: Day 3

1:00 pm - 2:40 pm: Lecture #7

Exercise and the Microbiome: Gut-Muscle Axis in Health and Disease
Gut barrier integrity and systemic health
Impact of exercise on gut microbial diversity and SCFA production
Role of prebiotics, probiotics, and synbiotics in supporting exercise outcomes
Microbiome’s role in systemic inflammation and recovery
Leveraging Nutritional Strategies, Amino Acids, and Protein for Muscle Health
Amino acid balance for muscle protein synthesis (MPS)
Timing and quality of protein intake for different types of exercise
Practical guidelines for protein needs based on training intensity, goals, and age

2:55 pm - 4:35 pm: Lecture #8

Exercise as an Anti-Cancer and Anti-Aging Strategy
Exercise-induced modulation of the tumor microenvironment
Key pathways: AMPK, mTOR, and autophagy in cancer prevention
Exercise and its impact on cellular senescence and telomere health
Strategies for integrating exercise in cancer prevention and management
Integrating Peptides, Repurposed Drugs, and Supplements in Exercise Programs
Peptides for performance and recovery: IGF-1, GHRH/GHRPs, and more
Repurposed drugs: Metformin, rapamycin, and senolytics in healthspan optimization
Supplements: Omega-3s, vitamin C, polyphenols, others and their role in enhancing exercise outcomes

4:50 pm - 6:30 pm: Lecture #9

Conclusion: Personalized Exercise Programs for Healthspan Optimization
Designing exercise prescriptions based on individual metabolic profiles
Integrating peptides, repurposed drugs, and nutritional strategies
Monitoring biomarkers and metrics for long-term adaptation and healthspan enhancement
Creating a practical roadmap for clinicians and patients to implement personalized exercise and therapeutic strategies.

Highlights From Our Vail 2023 Mastermind

FAQs

What does in-person registration for Mastermind 12 include?

The daily agenda for the in-person event is as follows:

7:00 am – 8:00 am: Breakfast
8:30 am – 11:30 am: Ski Morning
12:00 pm – 1:00 pm: Lunch
1:00 pm – 2:40 pm: Session #1
2:40 pm – 2:55 pm: Break #1
2:55 pm – 4:35 pm: Session #2
4:35 pm – 4:50 pm: Break #2
4:50 pm – 6:30 pm: Session #3
(Day 2 only) 7:00 pm – 9:00 pm: Reception Dinner & Networking

What does the pre-order for Mastermind 12 Digital include?

The pre-order for Mastermind 12 Digital On-Demand will include all event recordings, slides, and materials covered during the event. You will have lifetime access to all materials, as well as any updates made to the materials used.

What is the daily agenda for the event?

December 5th

7:00 am – 8:00 am: Breakfast
8:30 am – 11:30 am: Ski Morning
12:00 pm – 1:00 pm: Lunch
1:00 pm – 2:40 pm: Session #1
2:40 pm – 2:55 pm: Break #1
2:55 pm – 4:35 pm: Session #2
4:35 pm – 4:50 pm: Break #2
4:50 pm – 6:30 pm: Session #3

December 6th

7:00 am – 8:00 am: Breakfast
8:30 am – 11:30 am: Ski Morning
12:00 pm – 1:00 pm: Lunch
1:00 pm – 2:40 pm: Session #1
2:40 pm – 2:55 pm: Break #1
2:55 pm – 4:35 pm: Session #2
4:35 pm – 4:50 pm: Break #2
4:50 pm – 6:30 pm: Session #3
7:00 pm – 9:00 pm: Reception Dinner & Networking

December 7th

7:00 am – 8:00 am: Breakfast
8:30 am – 11:30 am: Ski Morning
12:00 pm – 1:00 pm: Lunch
1:00 pm – 2:40 pm: Session #1
2:40 pm – 2:55 pm: Break #1
2:55 pm – 4:35 pm: Session #2
4:35 pm – 4:50 pm: Break #2
4:50 pm – 6:30 pm: Session #3

Is there a group rate at the Four Seasons?

Attendees can take advantage of a heavily-discounted group room rate at the Four Seasons Resort & Residences Vail. The group rate is $485 per night plus all applicable taxes and fees, significantly reduced from the current rate of $937 per night.

Which airport should I fly into/out of?

We recommend flying into either Denver (DEN) or Eagle/Vail (EGE) airports.

Is transportation to/from the airport included?

We are offering complimentary airport pickup and travel to either DEN or EGE as part of your Mastermind 12 registration.

Are group activities covered in my registration?

We are offering 3 days of complimentary VIP guided ski lessons with private instructors as part of your Mastermind 12 registration.

Equipment rentals and any gear are not included as part of your registration.

How many attendees can register for Mastermind 12?

We limit attendance to SSRP Masterminds to ensure more in-depth collaboration between faculty and attendees. Mastermind 12 will be limited to approximately 50 attendees.

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Mastermind 12: Exercise Metabolism & Performance