Good evening everyone. I was looking for some advice on a patient regarding a protocol I am wanting to implement. The patient is a 61 y/o female who had been having years of generalized joint pain, HTN, Diabetes, and persistently elevated hs CRP levels in the mid to upper teens. She was eventually diagnosed with relapsing polychondritis, a rare autoimmune disease, which eventually caused her to have coronary artery and b/l renal stent placements. She is currently being treated by Mayo clinic and was placed on Humira, which controlled her pain and other symptoms for some time, but over the last few months she has been having break-through pain, and she began to look for alternative therapies, with an interest in peptides. We started her on TA1 initially with BPC157 and she was getting relief from her symptoms, in combination with an elimination diet., and optimized on hormone therapy. However, since TA1 is no longer available I was thinking of implementing the following protocol:
For the first three months to clear senescent burden:
-Rapamycin 2mg po once weekly
-Quercetin/dasatinib: 400/30, one capsule 3 days monthly (would you recommend giving while on Humira?)
-Epicatechin 500mg po qd for three weeks on then one week off.
-TA1 when available
After 3 months add in:
-NMN 500-1g orally daily
-NAD+ infusion
-Sermorelin 300mcg sq M-F qhs
-MOTS-C
Thank you for your time, much appreciated,
Patrick