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In this episode of Redox Revolution, Dr. Seeds discusses the lasting effects of Lyme Disease and the newest treatments that may offer answers and relief to the 450k+ Americans who are infected each year by Lyme Disease.
Office Hours PWC26 Virtual Summit Part 2 – Episode 100
- Evaluating terrain of the patient (1:43)
- SS31 peptide in practice (8:50)
- Phenotyping the right patient for GLP-1 therapy (11:18)
In this episode of Redox Revolution, Dr. Seeds follows up on the surprising effects of stress on the body and brain. He answers such questions as: why is stress necessary for brain functioning? What are the conditions to maximize the positive effects of stress? How can we “flip” stress from being a negative to a positive?
Office Hours: PWC26 Virtual Summit Part 1 – Episode 099
This special edition of Office Hours features questions submitted during the Peptide World Congress Virtual Summit on July 10 and 11. Dr. Seeds and Dr. Newman address:
- GLOW Stack, MOTS c, and Thyroid Function (0:50)
- Should the GLOW Stack Be Separated? (3:31)
- Peptides in Transplant Medicine (8:02)
- Biomarker Monitoring (13:21)
- Peptides in Acute and Long Term Stroke Recovery (17:37)
- Autoimmunity and the GI Tract (23:00)
- Cancer Concerns Related to Hormones and Angiogenesis (26:49)
In this episode of Redox Revolution, Dr. Seeds explores the benefits and costs of stress on the body. He delves into why the body needs stress, how too much stress harms the body, and how best to optimize stress levels for metabolic efficiency and cellular performance.
Pentosan Polysulfate: Dosing, Safety, and Monitoring
Dr. Seeds examines the subcutaneous use of pentosan polysulfate, addressing concerns about injection site scarring and ocular safety. He discusses dosing, site rotation, cumulative exposure, retinal screening, and strategies for responsible, individualized treatment.(Question Link)
In this episode, Dr. Seeds welcomes Sal Di Stefano, one of the founders of the hugely popular MindPump podcast to shed light on the truth about fitness, supplements, and peptides.
Creatine: Evidence, Pathways, and Hype
Dr. Seeds examines creatine through a cellular medicine lens, separating evidence-supported uses in ATP buffering, performance, and methylation from claims that exceed current clinical data.
In this episode of Redox Revolution, Dr. Seeds breaks down what you should know about your blood pressure, one of the most important modifiable risk factors.
Efficient Generation of Pancreatic Progenitor Cells from Induced Pluripotent Stem Cells Derived from a Non-Invasive and Accessible Tissue Source—The Plucked Hair Follicle
Dr. Seeds reviews how cryopreserved hair follicles may offer a simpler, non-invasive source for future stem cell research and pancreatic cell development. (Article Link)
Kelli Musa returns to unpack her Self-Led Woman framework, mapping how hormonal, metabolic, neurological, and cellular systems collide during perimenopause and menopause. Dr. Seeds ties the discussion to mitochondrial biogenesis and cellular decision-making, while the group explores GLP-1s, BPC-157, and TB-500 for weight, inflammation, and tissue repair.
Dr. Seeds’ Office Hours – Episode 095
1. Sjögren’s, POTS, Mold, Biofilms & Lumbrokinase (0:45)
2. PMDD, Allopregnanolone & Mitochondrial Efficiency (7:28)
3. Retatrutide, Glucagon & Metabolic Flexibility (20:01)
Functional wellness practitioner Kelli Musa joins the show to challenge how mainstream medicine handles women's hormonal health. The conversation revisits the misread 2002 hormone study, the difference between normal and optimal hormone levels, and how cortisol, estrogen, and progesterone work as an interconnected system through perimenopause and beyond.
Cellular Optimization for EDS Surgical Support
Dr. Seeds reviews peptide and supplemental considerations for cellular optimization in an EDS patient preparing for orthopedic surgery. (Question Link)
Recorded live at Peptide World Congress 2026, Dr. William Seeds makes the case against symptom-based medicine and walks through how cells actually make decisions: sensing redox balance, allocating energy through AMPK and mTOR, activating NRF2 antioxidant defenses, and protecting mitochondrial DNA. A phenotype-guided framework for cellular optimization.
The Phosphatidylcholine Pathway
Dr. Seeds expands on Journal Club Episode 92 to explore the role of phosphatidylcholine in lipid metabolism, methylation, and mitochondrial integrity during aging. He also highlights how estrogen loss may impact this pathway, especially in pre- and post-menopausal women.