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ARTICLE
William Seeds, MD
Sep 23, 2026
The Future of Regenerative Medicine May Begin with a Hair Follicle
William Seeds, MD Sep 23, 2026
The Future of Regenerative Medicine May Begin with a Hair Follicle
Why a Plucked Hair Follicle May Matter to the Future of Regenerative Medicine In this article, I return to a study that I discussed in a July Journal Club post. The study, published in Cells in 2024, investigated whether cells obtained from plucked, cryopreserved human hair follicles could be reprogrammed into induced pluripotent stem cells […]
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PODCAST
Redox Revolution
Sep 22, 2026
Ep.78 – Do Peptides Cause Cancer? The Risks, The Myths, And The Evidence
Ep.78 – Do Peptides Cause Cancer? The Risks, The Myths, And The Evidence

In this episode, Dr. Seeds addresses the many misunderstandings related to peptides and cancer.

Cellular Medicine Foundations · Peptides & Protocols
Peptide Therapy Certification 2026
The SSRP Peptide Therapy Certification course gives clinicians, researchers, and other healthcare providers a working method for applying Cellular Medicine principles to patient care through clinical peptide therapy. Across 19 faculty-led lessons, Dr. William Seeds and SSRP faculty, including Siobhan...
19 Lessons
15 hrs 43 min
View Course
VIDEO
Cellular Medicine Mondays
Sep 21, 2026
Ep. 106 - Peptide Support After Transplant: What to Consider First
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Dissecting Protocols – Episode 106

Peptide Support After Transplant: What to Consider First

Dr. Seeds explores how to protect graft integrity and identify the right cellular targets before considering peptide support in a patient six years post liver transplant.

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PODCAST
Redox Revolution
Sep 15, 2026
Ep.77 – Enhancing Orthopedic Outcomes and Improving Healing in Patients with Dr. Rahman
Ep.77 – Enhancing Orthopedic Outcomes and Improving Healing in Patients with Dr. Rahman

Dr. Seeds sits down with Omar Rahman, M.D. to talk about how peptide therapy can enhance orthopedic outcomes and speed up healing in patients.

Peptides & Protocols · Performance & Recovery
SSRP Institute Sep 14, 2026
In Case You Missed it: FDA Approves Mounjaro (tirzepatide) for CVD
HEADLINE SCIENCE [Sept 14, 2026] – On August 28, 2026, the FDA expanded the indication for Mounjaro (tirzepatide), approving the dual GIP/GLP-1 receptor agonist to reduce the risk of major adverse cardiovascular events—including cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke—in adults with type 2 diabetes at high cardiovascular risk. The decision makes tirzepatide the […]
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VIDEO
Cellular Medicine Mondays
Sep 14, 2026
Ep. 105 - Dr. Seeds’ Office Hours
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PODCAST
Redox Revolution
Sep 8, 2026
Ep.76 – Two Orthopedic Surgeons Discuss Cellular Medicine: Dr. Seeds and Dr. Rahman in Conversation
Ep.76 – Two Orthopedic Surgeons Discuss Cellular Medicine: Dr. Seeds and Dr. Rahman in Conversation

In this episode of Redox Revolution, Dr. Seeds welcomes orthopedic surgeon, Dr. Omar Rahman, who shares how he came to integrate cellular medicine and peptide therapy into his practice.

Longevity & Healthspan · Supplements & Nutrition
VIDEO
Cellular Medicine Mondays
Sep 7, 2026
Ep. 104 - Phenotyping is Essential to Cellular Medicine
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Rabbit Holes – Episode 104

Phenotyping is Essential to Cellular Medicine

In this episode of Rabbit Holes, Dr. Seeds breaks down why phenotyping is essential to Cellular Medicine. Understanding the individual patient allows for more precise, personalized care instead of guessing or relying on random peptide protocols.

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PODCAST
Redox Revolution
Sep 1, 2026
Ep.75 – Alcohol: The Facts about Use and Abuse
Ep.75 – Alcohol: The Facts about Use and Abuse

In this episode of Redox Revolution, Dr. Seeds addresses the misinformation about alcohol and clarifies common misunderstandings related to alcohol’s immediate and long-term effects on the brain and the body and the distinctions between abuse and addiction.

Brain & Cognition · Longevity & Healthspan
VIDEO
Cellular Medicine Mondays
Aug 31, 2026
Ep. 103 - Liposomal Peptides
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Dissecting Protocols – Episode 103

Liposomal Peptides

Dr. Seeds takes a closer look at liposomal peptides, including Epitalon, BPC-157, TB4, KPV, and GHK-Cu, and examines the claims around sourcing, stability, absorption, bioavailability, injection fatigue, and whether these formulations can truly compare to injectable peptides.

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SSRP Institute Aug 27, 2026
Rasonque: An FDA-Approved Drug to Treat Pancreatic Cancer
HEADLINE SCIENCE [August 27, 2026] – The Food and Drug Administration on Wednesday approved daraxonrasib, sold as Rasonque, for adults with metastatic pancreatic adenocarcinoma, the most common form of pancreatic cancer and one long considered among the hardest to treat. The once-daily tablet, developed by Revolution Medicines, is the first targeted therapy approved for the […]
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PODCAST
Redox Revolution
Aug 25, 2026
Ep.74 – Girls and Sports Injuries: Is There An Epidemic We’re Not Paying Attention To?
Ep.74 – Girls and Sports Injuries: Is There An Epidemic We’re Not Paying Attention To?

In this episode of Redox Revolution, Dr. Seeds discusses the rising prevalence of sports-related injuries in young women and girls. Why this increase? What’s at stake?

Performance & Recovery · Women's Health
VIDEO
Cellular Medicine Mondays
Aug 24, 2026
Ep. 102 - Office Hours: PWC26 Virtual Summit Part 4
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Office Hours PWC26 Virtual Summit Part 4 – Episode 102

Office Hours PWC26 Virtual Summit Part 4- Episode 102

  1. Compounded topical creams and GHK-Cu with microneedling (0:59)
  2. Detoxing before using copper (12:09)
  3. Patient onboarding process (12:54)
  4. Zinc and iron supplementation with GHK-Cu (23:41)
  5. Loss of taste after COVID (25:55)
  6. 3D CT scans for root canals (27:03)
  7. Oral bacteria swabs and GLP-1 effectiveness (28:00)
  8. Endocannabinoid system (29:07)
  9. GHK-Cu efficacy on wound beds (32:05)

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SSRP Institute Aug 21, 2026
Alpha-Gal Syndrome: An Update on Incidence Rate by the CDC
HEADLINE SCIENCE [August 21, 2026] – JAMA recently published a report about the incidence rate of alpha-gal syndrome, which is a serious allergic reaction to a sugar molecule called alpha-gal, which is found in most mammals. It is typically transmitted through a bite from a Lone Star tick or other tick species that injects the […]
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PODCAST
Redox Revolution
Aug 18, 2026
Ep.73 – Understanding Hearing Loss as We Age
Ep.73 – Understanding Hearing Loss as We Age

In this episode of Redox Revolution, Dr. Seeds examines hearing loss, the factors that cause significant loss, and what we can do now to prevent it.

Longevity & Healthspan
VIDEO
Cellular Medicine Mondays
Aug 17, 2026
Ep. 101 - Office Hours: PWC26 Virtual Summit Part 3
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Office Hours PWC26 Virtual Summit Part 3 – Episode 101

Office Hours PWC26 Virtual Summit Part 3 – Episode 101

1. Mitochondrial peptides (1:07)
2. MOTS-c cycle (3:50)
3. Injury site specific injection (9:25)
4. BPC-157 dosing (15:18)
5. Trusted labs (20:56)
6. What “redox” means (25:48)
7. Patient with cervical fusion, pain, and decreased range of motion (31:36)
8. Lipedema (37:03)
9. SS-31 and MOTS-c (37:52)
10. NanoVI device (44:49)
11. NAD (48:13)

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IntellxxDNA Aug 12, 2026
SSRP Institute Welcomes IntellxxDNA as New Trusted Partner
PARTNER ANNOUNCEMENT WILLOUGHBY, Ohio, [August 12, 2026] — The SSRP Institute welcomes IntellxxDNA to its Trusted Partner Network following a nomination and internal vetting process, aligning with SSRP’s mission to advance science-first, education-driven clinical collaboration. IntellxxDNA provides clinicians with a structured genomic decision support platform that translates complex genetic data into clinically actionable insights. Using […]
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PODCAST
Redox Revolution
Aug 11, 2026
Ep.72 – What You Need to Know About Lyme Disease
Ep.72 – What You Need to Know About Lyme Disease

In this episode of Redox Revolution, Dr. Seeds discusses the lasting effects of Lyme Disease and the newest treatments that may offer answers and relief to the 450k+ Americans who are infected each year by Lyme Disease.

Longevity & Healthspan
VIDEO
Cellular Medicine Mondays
Aug 10, 2026
Ep. 100 - Office Hours: PWC26 Virtual Summit Part 2
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Office Hours PWC26 Virtual Summit Part 2 – Episode 100

Office Hours PWC26 Virtual Summit Part 2 – Episode 100

  1. Evaluating terrain of the patient (1:43)
  2. SS31 peptide in practice (8:50)
  3. Phenotyping the right patient for GLP-1 therapy (11:18)

 

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ARTICLE
William Seeds, MD
Aug 6, 2026
A Lipid at the Root of Mitochondrial Aging: Phosphatidylcholine, Methylation, and a Malleable Therapeutic Window
William Seeds, MD Aug 6, 2026
A Lipid at the Root of Mitochondrial Aging: Phosphatidylcholine, Methylation, and a Malleable Therapeutic Window
Mitochondrial dysfunction is one of the most firmly established hallmarks of aging, but the field has spent far more energy describing genetic causes of mitochondrial failure—mtDNA mutation, defective OXPHOS, impaired unfolded protein response—than the “natural” drivers that erode mitochondria during ordinary aging. As I discussed in my recent June Journal Club (as well as a […]
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PODCAST
Redox Revolution
Aug 4, 2026
Ep.71 – The Surprising Effects of Stress On The Brain
Ep.71 – The Surprising Effects of Stress On The Brain

In this episode of Redox Revolution, Dr. Seeds follows up on the surprising effects of stress on the body and brain. He answers such questions as: why is stress necessary for brain functioning? What are the conditions to maximize the positive effects of stress? How can we “flip” stress from being a negative to a positive?

Brain & Cognition
VIDEO
Cellular Medicine Mondays
Aug 3, 2026
Ep. 099 - Office Hours: PWC26 Virtual Summit Part 1
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Office Hours: PWC26 Virtual Summit Part 1 – Episode 099

Office Hours: PWC26 Virtual Summit Part 1 – Episode 099

This special edition of Office Hours features questions submitted during the Peptide World Congress Virtual Summit on July 10 and 11. Dr. Seeds and Dr. Newman address:

  1. GLOW Stack, MOTS c, and Thyroid Function (0:50)
  2. Should the GLOW Stack Be Separated? (3:31)
  3. Peptides in Transplant Medicine (8:02)
  4. Biomarker Monitoring (13:21)
  5. Peptides in Acute and Long Term Stroke Recovery (17:37)
  6. Autoimmunity and the GI Tract (23:00)
  7. Cancer Concerns Related to Hormones and Angiogenesis (26:49)

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PODCAST
Redox Revolution
Jul 28, 2026
Ep.70 – The Benefits and Costs of Stress on The Body
Ep.70 – The Benefits and Costs of Stress on The Body

In this episode of Redox Revolution, Dr. Seeds explores the benefits and costs of stress on the body. He delves into why the body needs stress, how too much stress harms the body, and how best to optimize stress levels for metabolic efficiency and cellular performance.

Longevity & Healthspan
VIDEO
Cellular Medicine Mondays
Jul 27, 2026
Ep. 098 - Pentosan Polysulfate: Dosing, Safety, and Monitoring
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Dissecting Protocols – Episode 098

Pentosan Polysulfate: Dosing, Safety, and Monitoring

Dr. Seeds examines the subcutaneous use of pentosan polysulfate, addressing concerns about injection site scarring and ocular safety. He discusses dosing, site rotation, cumulative exposure, retinal screening, and strategies for responsible, individualized treatment.(Question Link)

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SSRP Institute Jul 24, 2026
PCAC Meeting Vote Summary
BREAKING NEWS JULY 24, 2026 – The Pharmacy Compounding Advisory Committee (PCAC) has completed its July session, voting on several peptide bulk drug substances for potential inclusion on the FDA’s 503A Bulks List.Recommended FOR inclusion: (Yes-No)• BPC-157 (8–6)• KPV (8–6)• TB-500 (8–6)• MOTS-c (7–5)• Epitalon (7–4)• Semax (8–5)Recommended AGAINST inclusion: (Yes-No)• DSIP (6–7) What happens […]
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PODCAST
Redox Revolution
Jul 21, 2026
Ep.69 – Brain Dump: Mind Pumping Your Way to Better Health, With Sal Di Stefano
Ep.69 – Brain Dump: Mind Pumping Your Way to Better Health, With Sal Di Stefano

In this episode, Dr. Seeds welcomes Sal Di Stefano, one of the founders of the hugely popular MindPump podcast to shed light on the truth about fitness, supplements, and peptides.

Brain & Cognition
VIDEO
Cellular Medicine Mondays
Jul 20, 2026
Ep. 097 - Creatine: Evidence, Pathways, and Hype
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Rabbit Holes – Episode 097

Creatine: Evidence, Pathways, and Hype

Dr. Seeds examines creatine through a cellular medicine lens, separating evidence-supported uses in ATP buffering, performance, and methylation from claims that exceed current clinical data.

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ARTICLE
William Seeds, MD
Jul 14, 2026
The Renin–Angiotensin–Aldosterone System (RAAS): Beyond Blood Pressure Regulation
William Seeds, MD Jul 14, 2026
The Renin–Angiotensin–Aldosterone System (RAAS): Beyond Blood Pressure Regulation
After a recent Journal Club episode in which I featured, The Renin–Angiotensin–Aldosterone System (RAAS): Beyond Cardiovascular Regulation, I wanted to return to the article and expand a bit on the significance of the Renin–Angiotensin–Aldosterone System (RAAS). As we know, the RAAS system has traditionally been viewed as the body’s primary mechanism for regulating blood pressure, […]
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PODCAST
Redox Revolution
Jul 14, 2026
Ep.68 – Blood Pressure: Tracking Yours and What It Means
Ep.68 – Blood Pressure: Tracking Yours and What It Means

In this episode of Redox Revolution, Dr. Seeds breaks down what you should know about your blood pressure, one of the most important modifiable risk factors.

Longevity & Healthspan
Peptide World Congress 2026
At Peptide World Congress 2026, join the fastest-growing community of evidence-based providers exploring the therapeutic power of clinical peptides. Learn why the body ages, when disease originates, and how top clinicians are changing their patients’ lives by treating the body...
22 Lessons
13 hrs 10 min
View Course
VIDEO
Cellular Medicine Mondays
Jul 13, 2026
Ep. 096 - Stem Cells Derived from The Plucked Hair Follicle
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Journal Club – Episode 096

Efficient Generation of Pancreatic Progenitor Cells from Induced Pluripotent Stem Cells Derived from a Non-Invasive and Accessible Tissue Source—The Plucked Hair Follicle

Dr. Seeds reviews how cryopreserved hair follicles may offer a simpler, non-invasive source for future stem cell research and pancreatic cell development. (Article Link)

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PODCAST
Redox Revolution
Jul 7, 2026
Ep.67 – Reframing Midlife with Kelli Musa
Ep.67 – Reframing Midlife with Kelli Musa

Kelli Musa returns to unpack her Self-Led Woman framework, mapping how hormonal, metabolic, neurological, and cellular systems collide during perimenopause and menopause. Dr. Seeds ties the discussion to mitochondrial biogenesis and cellular decision-making, while the group explores GLP-1s, BPC-157, and TB-500 for weight, inflammation, and tissue repair.

Peptides & Protocols · Women's Health
VIDEO
Cellular Medicine Mondays
Jul 6, 2026
Ep. 095 - Dr. Seeds’ Office Hours
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Dr. Seeds’ Office Hours – Episode 095
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ARTICLE
Scott Sherr, MD
Jul 2, 2026
Methylene Blue: From Cellular Energy to Clinical Practice
Scott Sherr, MD Jul 2, 2026
Methylene Blue: From Cellular Energy to Clinical Practice
Scott Sherr, MD | Lucía González Forte, PhD  Submitted for publication [Article] to the SSRP Institute Abstract Methylene blue (MB) is a century-old compound whose renewed relevance in clinical medicine reflects a clearer understanding of its role in mitochondrial function, redox biology, and neuroinflammatory signaling. At therapeutic oral doses, MB acts as a catalytic electron […]
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The Self-Led Woman
If you are in midlife and feel like your body stopped following the rules it used to, this course is for you. The premise is simple: your body is not broken. It is running a different program than the one...
9 Lessons
1 hr 28 min
View Course
The Cell Code
A Cellular Medicine Perspective on Health, Aging, and Disease Cell Code is a structured walk through ten core molecular pathways that shape Cellular Medicine. For each pathway, the course presents twenty questions, beginning with foundational mechanisms and moving into applied...
31 Lessons
Self-paced
View Course
SSRP Institute Jun 10, 2026
PCOS Name Change to PMOS: Polyendocrine Metabolic Ovarian Syndrome
HEADLINE SCIENCE [JUNE 10, 2026] – An international body of medical scientists in obstetrics and gynecology, endocrinology, and other speciality societies, and other physicians announced the result of a multi-year process to formally change the name of Polycystic Ovary Syndrome (PCOS) to Polyendocrine Metabolic Ovarian Syndrome (PMOS). This change, published in May 2026 in The […]
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ARTICLE
William Seeds, MD
Jun 3, 2026
GLP-1 and the Gut–Musculoskeletal Axis: A Clinical Summary
William Seeds, MD Jun 3, 2026
GLP-1 and the Gut–Musculoskeletal Axis: A Clinical Summary
The Overlooked Connection: Dysbiosis and Degenerative Disease Degenerative musculoskeletal diseases, including osteoarthritis (OA), osteoporosis (OP), sarcopenia (SP), and intervertebral disc degeneration (IVDD), affect well over a billion people globally and share three core pathological features: chronic inflammation, oxidative stress, and dysregulated cell death. What is increasingly clear, and clinically underappreciated, is that gut microbiota (GM) […]
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Peptide Therapy Foundations: Skin Resilience
This course examines the peptides applied to the skin and its appearance: the topical signal peptides that influence collagen and expression lines, the copper-binding repair peptide, and the melanocortin agonists that act on pigmentation. It is written for clinicians who...
6 Lessons
3 hrs 5 min
View Course
Peptide Therapy Foundations: Hormonal & Sexual Health
This course examines the peptides that act on sexual function and the hormonal axis that governs reproduction. It is written for clinicians who want to understand how these agents influence desire, arousal, and the upstream signaling of the reproductive system,...
3 Lessons
2 hrs 10 min
View Course
Peptide Therapy Foundations: Sleep Hygiene
This course examines the peptides connected to sleep and the nighttime environment: the agents studied for their influence on sleep architecture, melatonin signaling, and the restorative processes that occur overnight. It is written for clinicians who want to understand how...
3 Lessons
1 hr 55 min
View Course
Peptide Therapy Foundations: Circadian Rhythms
This course examines the peptides connected to the body’s daily clock: the pineal-derived regulators and signaling peptides studied for their influence on circadian rhythm, sleep-wake timing, and the aging of the timekeeping system. It is written for clinicians who want...
3 Lessons
2 hrs 4 min
View Course
Peptide Therapy Foundations: Recovery & Gut Stabilization
This course examines the peptides used in the service of repair and recovery: the agents studied for tissue healing, inflammation control, and the integrity of the gut barrier. It is written for clinicians who want a grounded understanding of how...
12 Lessons
7 hrs 39 min
View Course
Peptide Therapy Foundations: Neuroprotection
This course examines the peptides studied for their effects on the brain: the regulatory peptides, neurotrophic preparations, and growth-factor analogs explored for cognition, mood, and neural resilience. It is written for clinicians who want a grounded understanding of how each...
9 Lessons
5 hrs 45 min
View Course
Peptide Therapy Foundations: Immune Regulation
This course examines the peptides that shape immune function: the thymic peptides that help regulate the maturation and balance of the immune response, and the host-defense peptides that act at the front line of innate immunity. It is written for...
5 Lessons
3 hrs 1 min
View Course
Peptide Therapy Foundations: Mitochondrial Health
This course examines the peptides that act at the level of the mitochondria: the small molecules and mitochondrial-derived peptides that influence energy production, oxidative balance, and cellular signaling. It is built for clinicians who want to understand how these agents...
3 Lessons
2 hrs 14 min
View Course
GuardianMD May 21, 2026
SSRP Institute Welcomes GuardianMD as New Trusted Partner
PARTNER ANNOUNCEMENT WILLOUGHBY, Ohio, [May 21, 2026] — The SSRP Institute announces that GuardianMD has joined its Trusted Partner Network following nomination and completion of the SSRP’s internal review process. GuardianMD is a healthcare services organization focused on physician collaboration and medical direction. It also provides telemedicine clearance services for healthcare practices. The company supports […]
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ARTICLE
William Seeds, MD
May 14, 2026
How the Peptide AOD-9604 Targets LanCL Proteins to Fight Viral Infections and Neurodegenerative Conditions 
William Seeds, MD May 14, 2026
How the Peptide AOD-9604 Targets LanCL Proteins to Fight Viral Infections and Neurodegenerative Conditions 
In this research article, I return to the subject of my first-ever Journal Club (Ep. 017), in which I discussed a 2023 research study entitled, “Naturally derived cytokine peptides limit virus replication and severe disease during influenza A virus infection” (2023) that examined a specific growth hormone-derived peptide to address the underlying immunological mechanisms of post-viral […]
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SSRP Institute May 6, 2026
Nutrition Education for Physicians and Medical Students
HEADLINE SCIENCE MAY 6, 2026 —Earlier in March, the U.S. Department of Health and Human Services (HHS) and the U.S. Department of Education announced an initiative to emphasize nutrition at the nation’s top medical schools. Reflecting U.S. Health and Human Services Secretary Robert Kennedy’s commitment to preventative medicine, this initiative will require “meaningful nutrition training” […]
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SSRP Institute Apr 29, 2026
New ACC and AHA Cholesterol Management Guidelines
HEADLINE SCIENCE [APRIL 29, 2026] – The American College of Cardiology (ACC) and American Heart Association (AHA) have updated their cholesterol management guidelines, advocating for earlier and more aggressive intervention based on the understanding that cumulative lifetime exposure to high LDL-C drives atherosclerotic cardiovascular disease (ASCVD) risk. The guidelines aim to standardize care for dyslipidemia […]
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ARTICLE
William Seeds, MD
Apr 21, 2026
A Review of Circadian Processes and Evidence-Based Interventions to Improve Sleep
William Seeds, MD Apr 21, 2026
A Review of Circadian Processes and Evidence-Based Interventions to Improve Sleep
Introduction In March of this year, I did a Rabbit Hole (Episode 079) in which I discussed a number of trends marketed to the wider public promising sleep improvement. As you know, a huge swath of the population suffers from sleep disturbance. According to the NIH, approximately 30% to 40% of US adults report sleep […]
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SSRP Institute Apr 15, 2026
FDA Announces Change in Status of 12 Peptides
BREAKING NEWS APRIL 15, 2026 – In a welcome announcement to the SSRP Community, the FDA reported today that it will imminently remove the following bulk drug substances from category 2: BPC-157, LL-37, DiHexa, DSIP, Epitalon, *GHK-Cu (injectable only), KPV, PEG-MGF, Melanotan II, MOTs-C, Semax, and TB-500. Originally nominated for Category 2 (Bulk Substances that […]
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SSRP Institute Apr 9, 2026
SSRP Institute Welcomes StemWave as New Trusted Partner
PARTNER ANNOUNCEMENT WILLOUGHBY, Ohio, [April 9, 2026] — The SSRP Institute announces that StemWave has joined its Trusted Partner Network following nomination and completion of the SSRP’s internal review process. StemWave provides an FDA-listed, non-invasive acoustic wave therapy platform used in musculoskeletal care. The technology delivers focused mechanical energy to targeted tissues, supporting improved circulation, […]
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Medivive Mar 27, 2026
SSRP Institute Welcomes Medivive as New Trusted Partner
PARTNER ANNOUNCEMENT WILLOUGHBY, Ohio, [March 27, 2026] — The SSRP Institute is pleased to announce that Medivive has joined its Trusted Partner Network following nomination and internal vetting aligned with SSRP’s mission of advancing science-first, education-driven clinical collaboration. Medivive offers an advanced approach to NAD⁺ therapy designed to support cellular energetics through sterile, clinician-prescribed formulations […]
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ARTICLE
William Seeds, MD
Mar 25, 2026
The Truth about Ketone Esters: Not All Exogenous Products are the Same
William Seeds, MD Mar 25, 2026
The Truth about Ketone Esters: Not All Exogenous Products are the Same
The Father of Ketones and the Value of Exogenous Ketone Esters I’ve talked about ketones and ketone esters for many years, and I’ve now come to a place  where I really have to take a more direct stand on how they’ve been marketed to the wider public, and in particular, to providers who may not […]
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ARTICLE
William Seeds, MD
Feb 26, 2026
The Role of Spermidine and Endothelial Regeneration
William Seeds, MD Feb 26, 2026
The Role of Spermidine and Endothelial Regeneration
Recently I presented a Rabbit Hole (1/19/2026) related to the polyamine, spermidine, in response to a 2025 article, “Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis,” which appeared in Nature Cell Biology. I was fascinated by the premise of this study because it not only provides a mechanistic way of looking at […]
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ARTICLE
William Seeds, MD
Jan 20, 2026
Microglia
William Seeds, MD Jan 20, 2026
Microglia
Microglia are the brain’s resident immune cells — but they’re much more than just defenders. Think of them as a combination of janitors, gardeners, and neighborhood watch patrols that keep the brain healthy, balanced, and adaptable. The Brain’s First Responders Microglia constantly patrol the brain, extending and retracting their tiny branches like radar antennas. When […]
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ARTICLE
William Seeds, MD
Dec 17, 2025
The Brain and Exercise: How Different Forms of Exercise Impact Neuronal Metabolism and Neuroprotection
William Seeds, MD Dec 17, 2025
The Brain and Exercise: How Different Forms of Exercise Impact Neuronal Metabolism and Neuroprotection
Introduction Understanding brain metabolism offers insight not only into the potential root causes of neurodegenerative disease but also the interventions that can positively impact cognitive functioning. In particular, looking at the pathways, energy use, and factors of neuronal adaptation that happens in exercise offers us important insight into the basis of neuroprotection.  Let’s keep in […]
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ARTICLE
William Seeds, MD
Nov 12, 2025
Improving Biological Age with GLP-1 RAs: An Analysis of a Study 
William Seeds, MD Nov 12, 2025
Improving Biological Age with GLP-1 RAs: An Analysis of a Study 
This is a further dive into and expansion of a Journal Club video that I offered in September 2025 in response to a fascinating article related to the power of GLP-1 peptides to create positive epigenetic changes at the cellular level.  The study, Semaglutide Slows Epigenetic Aging in People with HIV-associated lipohypertrophy: Evidence from a Randomized […]
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Book
William A. Seeds, MD
Jun 3, 2025
The Quantum Power of GLP-1 Peptides​
The Quantum Power of GLP-1 Peptides​
The hype about GLP-1 drugs like Ozempic have clouded their importance beyond weight loss and treatment of type 2 diabetes. In The Quantum Power of GLP-1 Peptides: Unlocking the Science that Leads to Lasting Weight Loss and Optimal Healthspan, Dr. William A. Seeds uncovers the cellular mechanisms behind GLP-1s and other peptides that can effectively address heart disease, certain cancers, neurodegenerative diseases, autoimmune disorders, arthritis, and other inflammatory conditions.

In this third book, Dr. Seeds offers readers a concise guide to both the research and clinical applications of GLP-1s and other peptides. This book is intended to empower medical professionals and individuals who want to be part of a healthcare movement committed not only to longevity but to optimal healthspan.
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Book
William A. Seeds, MD
Aug 12, 2024
The Redox Promise
The Redox Promise
With The Redox Promise, Dr. William A. Seeds offers the first-ever evidence-based guide to the process of cellular redox — the oxidation-reduction cycles that provide cellular energy and have the power to resist disease and fight aging. When redox is in balance, we can halt the cellular mechanisms associated with aging poorly and the diseases that can but don’t have to develop, including heart disease, type 2 diabetes, metabolic disorders, cancer, neurodegenerative disease, and more.

Balancing cellular redox does not have to be complicated: it’s about giving the body what it needs with proper nutrients, eliminating waste, and maintaining cellular balance. By identifying 30 research-backed supplements that support redox balance, decrease inflammation, balance the gut’s microbiome, and empower the immune system, The Redox Promise provides practitioners and patients a powerful framework to protect health and extend healthspan.
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Book
William A. Seeds, MD
Aug 24, 2020
Peptide Protocols, vol. 1
Peptide Protocols, vol. 1
In his first book, Peptide Protocols, Volume One, Dr. William A. Seeds introduces the cellular mechanisms behind improving patient health with clinical peptides. As the foremost authority on why and how to use peptides to delay cellular senescence, reduce inflammation throughout the body and brain, and address the underlying mechanisms of aging, Dr. Seeds provides physicians and healthcare professionals with a foundational understanding of cellular function and the role of peptides in achieving better patient outcomes.

Supported by extensive peer-reviewed studies, Peptide Protocols offers insight and practical knowledge on how to support patients before, during, and after treatment. This groundbreaking Cellular Medicine approach to disease treatment and prevention has the potential to transform outcomes in patient care and change lives.
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