11 Replies

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• November 9, 2021 at 5:12 pm #31290
  Miguel Bertonatti

  Member

  SSRP Certified

  We had a patient misread the peptide instructions and injected 2000mcg of Ipamorelin 7x per week. The question is should the patient take a month off to reset the receptors or just adjust the dose and keep administering the peptide?

  November 11, 2021 at 4:10 pm #31291
  Kristelle Reyes

  Member

  SSRP Staff

  Hello @byurthgmail-com and @cpaigepaigemd-com, would love to have your insights here. Thank you! 🙂

  November 11, 2021 at 4:27 pm #31292
  Miguel Bertonatti

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  SSRP Certified

  Us too! Can’t wait.

  December 2, 2021 at 1:16 pm #31293
  Madison Lepore

  Member

  SSRP Certified

  Hello!

  GHRP has a saturation dose of about 100 mcg meaning above this you get minimal extra signaling with higher doses above saturation dose (In general but there are caveats to this statement)

  You do not need worry with Ipamorelin in the short term with involution or receptor desensitization. It is the long term continued stimulation of GHRP receptors (not GHRH) above saturation dose where this would be an issue (greater than 3 months).

  
  @michaelmedicalhealthinstitute-com

   

   

  December 2, 2021 at 6:33 pm #31294
  William Seeds, MD

  Member

  SSRP Staff

  thanks @madisonseeds-md =)

  February 7, 2022 at 8:25 am #31295
  Kristelle Reyes

  Member

  SSRP Staff

  Claim your CME here: https://earnc.me/o40ruB

  February 7, 2022 at 10:10 am #31296
  Miguel Bertonatti

  Member

  SSRP Certified

  Thank you @madisonseeds-md

  March 7, 2022 at 9:51 pm #31297
  Mary Ann Butler

  Member

  SSRP Certified

  What about doses of 200mcg.

  Many pharmacies are telling patients and providers that 200mcg daily will not desensitize the receptors.

  I’ve always followed Dr Seeds’ recommendations from years ago. Has the data changed?

  March 8, 2022 at 8:05 am #31298
  Miguel Bertonatti

  Member

  SSRP Certified

  Not that we know of. Dr. Seed protocol is 200mcg 1-3x per day.

  March 8, 2022 at 8:40 am #31299
  Leonard Pastrana

  Member

  SSRP Certified

  Quote from Mary Ann Butler on March 7, 2022, 9:51 pm

  What about doses of 200mcg.

  Many pharmacies are telling patients and providers that 200mcg daily will not desensitize the receptors.

  I’ve always followed Dr Seeds’ recommendations from years ago. Has the data changed?

  Recommendations are still the same. 100mcg 1-4 times daily depending on the desired outcome. We don’t worry about desensitization necessarily with higher doses like 2-300mcg  its just that the saturation dose is around 100mcg or 1mcg/kg and anything more normally doesn’t provide that much extra benefit.

  Nightly dosing: anti-aging, sleep, recovery, bone mineral density.

  BID dosing: fat loss

  TID dosing: enhanced fat loss and anabolism

  QID: Recovery, increased healing injury, IGF-1.(must be separated by at least 3 hours) Add BPC BID 300mcg

   

  I see the best results for body composition with multiple dosing per day. I do go up to 200mcg at bedtime if that’s their only dose for the day for patients just using as an overall anti-aging strategy.

  March 8, 2022 at 10:33 am #31300
  Miguel Bertonatti

  Member

  SSRP Certified

  Could we have pt’s do 200mcg of Ipamorelin TID? Or do you suggest dropping to 100mcg of Ipamorelin? We thought you can gain more benefits out of 200mgs? We understand that with CJC it should be 1mcg/kg or 100mcg 1-4 times a day? If we are wrong, could you please specify dosing for CJC separate from Ipamorelin?

   

  ALSO, with the “QID: Recovery, increased healing injury, IGF-1.(must be separated by at least 3 hours) Add BPC BID 300mcg” – Did you mean inject Ipamorelin 100mcg 3x per day along with an IGF-1 LR3 50-100mcg injection 1x per day?  3-4 hours apart?

   

  @Mary Ann Butler

  March 8, 2022 at 11:53 am #31301
  Leonard Pastrana

  Member

  SSRP Certified

  Quote from Miguel Bertonatti on March 8, 2022, 10:33 am

  Could we have pt’s do 200mcg of Ipamorelin TID?

  You can

  Or do you suggest dropping to 100mcg of Ipamorelin?

  I have gotten the results I was looking for with even bigger guys250 pound + with just 100mcg of both cjc and ipamorelin multiple daily dosing

   

  We thought you can gain more benefits out of 200mgs?

  This may be true but how much benefit and is it cost effective are the variables you have to weigh out. 

  We understand that with CJC it should be 1mcg/kg or 100mcg 1-4 times a day? If we are wrong, could you please specify dosing for CJC separate from Ipamorelin?

  We use the same amount for each. CJC/ipamorelin 100mcg/100mcg per dose. 

   

  ALSO, with the “QID: Recovery, increased healing injury, IGF-1.(must be separated by at least 3 hours) Add BPC BID 300mcg” – Did you mean inject Ipamorelin 100mcg 3x per day along with an IGF-1 LR3 50-100mcg injection 1x per day?  3-4 hours apart?

  No the IGF in that comment just means if you are looking for a bump in IGF you can get that with that dosing.  

  For a nice table that goes over dose dependent dosing of  GHRH/GHRP refer to page 64 of the Peptides Protocols book by Dr. Seeds.

   

  @Mary Ann Butler

   

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