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Testosterone administration, males

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Testosterone administration, males

Ethan Rohde January 24, 2022 at 6:03 pm

4 Replies

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  • #31472
    Ethan Rohde
    Member
    SSRP Certified

    Hello all,

    Curious thoughts on testosterone administration, method, and dose for males (topical and pellets for another day, also covered in prior posts here).

    Method: IM or SQ? IM seems the most used, but I like SQ for patient ease – thoughts on it depositing per oil base and adipose?

    Dose: 200mg per 14 days as standard dose – recommendations on daily, every 3rd day, once per week, etc?  Once every 2 weeks seems inappropriate if can be avoided.

    Forms: I’m only really using cypionate.

    Many thanks,

    Ethan

    #31473
    Kristelle Reyes
    Member
    SSRP Staff

    Hello @drkriswyahoo-com, @byurthgmail-com and @cpaigepaigemd-com, would love to have your insights here. Thank you! 🙂

    #31474
    Carl Paige, MD
    Member
    SSRP Certified

    If possible I try to recover natural Testosterone production with managing underlying medical/metabolic issues and use of KISSPEPTIN, and or enclomiphene or similar products.  If this is not practical, appropriate or ineffective  I use IM / SQ for those patients requiring replacement Testosterone.  For IM use of a cypionate, or enthanate oil once weekly minimum frequency or twice weekly IM to provide the smoothest coverage.  Also if the patient does not want IM delivery for whatever reason I will take the weekly dose divided by 7  and dispense SQ with excellent results.   Every 2 week dosing is not appropriate considering the 1/2 life of these products.

    Carl

    #31475
    Eric Fete
    Member
    SSRP Certified

    Agreed about underlying issues.  Once I start TRT- I use SC injections, typically 2 x per week.  The lower the SHBG the more frequent I dose.  Some do ok on once a week but 2-3 x a week is better (steady state, less peaks and valleys).  I have also had good success with topical application (scrotal application is best)- 100-200mg bid with a Versabase or Atrevis base cream.

    Eric

    #31476
    Kristelle Reyes
    Member
    SSRP Staff

    Claim your CME here: https://earnc.me/pigFaf

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