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Pentosan in L4/5 stenosis + Nitric Oxide

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Pentosan in L4/5 stenosis + Nitric Oxide

Alison Lechner May 4, 2025 at 6:58 am

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  • #36867
    Alison Lechner
    Member
    SSRP Certified
    Hello everyone, 
    I am relatively new to the group and to peptides I have a lot of questions, but will limit this post to 2 - unrelated Qs
    Thank you all for taking the time to share your expertise. 
    
    1/ 
    I am hoping to get some insight to determine if using PPS with chronic low back pain will be helpful in one of my patients.
    Recent L/S MRI shows diffuse mild central and foraminal stenosis, and at L4-5 there is a posterior ridge spur/complex with severe 
    central stenosis and severe bilateral degenerative neural foraminal stenosis. She has limited funds, but would 
    be willing to move forward with this may help. I assume she is looking at a procedure of some sort - so is there any value in 
    trying the Pentosan? 
    
    2/  Nitric oxide - 
    I have a few patients that I have not been able to improve NO levels ( using HumanN test strips). I have used the typical 
    products like Neo40, Vascanox, along with addressing oral microbiome and oral hygiene products, addressing HCY/ methylation pathways which are also
    hard to optimize in some but not all of these patients .. I understand that there may be some underlying issue as to why the NO production is suppressed 
    but I have one 60 yr old male who is generally healthy, coming to me for optimization and prevention. He has Erectile Dysfunction 
    that is not responding to numerous meds/ interventions. I see the connection between the low NO and ED..  His ADMA is normal, and 
    does not have anything that would suggest a chronic infection ( although now that I am writing this, I should check for COVID antibodies). 
    I just started him on niacin BPC and KPV... seems aggressive for an otherwise healthy male, so what am I missing? 
    
    Thank you all again! 
    
    Alison Lechner 
     
      
    
    
    #36868
    Kristelle Reyes
    Member
    SSRP Staff

    Hello @drlechnershinefunctionalhealth-com-2

    Here’s a video response from Dr. Seeds’ June 2025 Office Hours at 17:27. Please watch by clicking the link below:

    https://ssrpinstitute.org/ssrp-members-videos/

    Thank you! ?

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