19 Replies

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• September 25, 2020 at 2:29 pm #29113
  Mary Ann Butler

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  SSRP Certified

  I have read that 5-amino 1 MQ is recommended for only 20 days. Can anyone explain the rationale behind this? Is anyone else using 5-amino 1 MQ for weight loss? How are you all using it?

  Thank you,

  • Mary Ann
  September 28, 2020 at 5:00 pm #29114
  jason pencek

  Member

  SSRP Certified

  I use it for weight loss and overall energy increase in my patients. I had one woman lose 7# the first 30 days she took it. She loved it. Immediately after her first month, Tailor Made stopped making it. The handful of other patients that started on it all reported an overall improvement in well being generally. I have had numerous requests for this product for the last few months. Personally I use it for increasing my intracellular NAD while still doing NAD+ 100mg injections daily. I know Dr. Seeds no longer recommends the NAD+ injections but I find my workouts are better with the NAD+ daily injections.

  October 10, 2020 at 7:49 pm #29115
  Mary Ann Butler

  Member

  SSRP Certified

  Thank you, Jason for your response.  Do you cycle the 5-amino? Ryan had recommended in one of his webinars to only use for 20 days. However, I can not find anywhere the rationale.

  I did not know that Dr. Seeds no longer recommends NAD+ injections. Do you know why that is?

  October 18, 2020 at 8:54 am #29116
  Khanh Nguyen, MD

  Member

  SSRP Certified

  Hi Jason ,

  So you use NAD 100 mg subcut daily ?

  I have tried the patch from TMC twice and I had a skin reaction / burn both times anD IV is too intense and time consuming.

  October 18, 2020 at 10:29 am #29117
  Xan Simonson

  Participant

  SSRP Certified

  Hi Khanh,

  Recently I am using a NAD+ 250mg  SQ injection-1cc from Meta Pharmacy from Las Vegas, NV. IT has some other things in it such as BCAA, taurine, methylcobalamin. I didn’t have a reaction or feel that uncomfortable feeling you get with IV and the TMC patch. I tried it to and NO WAY will I give that to a patient.

  I think it is called NAD+ Limitless SQ injection. They have different strengths but after my experience with TMC product I chose the lowest dose.

  Xan

  October 18, 2020 at 1:00 pm #29118
  Mary Ann Butler

  Member

  SSRP Certified

  How are you dosing the 5-amino 1 mQ and NAD around meals?

  October 31, 2020 at 12:47 pm #29119
  Craig Koniver, MD

  Member

  SSRP Certified

  I’d be very cautious about utilizing a product that mixes NAD+ with other nutrients. It’s highly unstable and likely the reason you didn’t feel anything is because the NAD+ had broken down.

  We utilize Humanin (separately) at same time as NAD+ and that seems to be a worthwhile combo

  November 1, 2020 at 12:01 pm #29120
  Xan Simonson

  Participant

  SSRP Certified

  Dr. Koniver where do you get Humanin?

  In regards to the NAD+ Limitless Injection- It does help with increased energy and brain cognition. I take it myself as well as several of my patients whom love it.

   

  December 4, 2020 at 1:50 pm #29121
  Mitchell Fleisher, M.D., D.Ht., D.A.B.F.M.

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  SSRP Certified

  An excellent alternative peptide for weight loss in patients who refuse to do SQ injections is Ibutamoren mesylate (MK-677), taken 25 mg po qHS for 30, 60, or 90 days.  It is a relatively potent, oral GHRP that promotes bone and muscle anabolism and adipose catabolism.  It has been therapeutically successful, and very well-tolerated by a wide range of my patients.

  December 4, 2020 at 5:44 pm #29122
  jason pencek

  Member

  SSRP Certified

  Has anyone noticed the new 5 Amino 1MQ from other pharmacies such as Farmekio not being as potent as Tailor Made Compounding? I have two patients who loved 5 Amino when it first came out and have tried the new versions. They state the results are not the same.

   

  As far as MK-677 is concerned, I only use this in patients trying to put on muscle and weight. It works on the ghrelin pathway more than CJC/IPA does. Patients tend to get hungry. They feel the benefits of the growth hormone analog but also complain about being hungry and putting on weight. Just a caution for anyone trying to optimize for weight loss. Almost every patient I’ve put on MK-677 complains their weight has increased. I now use this instead of the GHRP-2/GHRP-6/Sermorelin combo I used to use for weight gain.

  December 5, 2020 at 4:34 pm #29123
  Neil Paulvin

  Member

  SSRP Certified

  Where are you getting mk from and what dose? I use mk all the time my patients love it for getting more muscle and losing weight.  I admit this is for some of my patients who can’t afford tessamorelin

  December 8, 2020 at 8:04 pm #29124
  jason pencek

  Member

  SSRP Certified

  Neil, I have used MK677 from Tailor Made when they used to carry it and have used it from Farmekio. Both times I had similar responses. My patients trying to put on weight love it. I just have a lot of patients who complain they are gaining weight on it. Strange it’s helping your patients lose weight. Hmmm…anyone else want to chime in?

  December 11, 2020 at 8:59 am #29125
  Leonard Pastrana

  Member

  SSRP Certified

  Going to be starting this soon myself. Will keep you posted. Going to get a DEXA scan before and after. So should have a good idea of where the weight is coming and going from.

  January 20, 2021 at 10:26 pm #29126
  Kent Holtorf

  Member

  SSRP Certified

  Hi Dr. Koinver,

  Was also wondering where you get humanin.

  Thanks so much,

  Kent
  May 11, 2022 at 9:24 am #29127
  Bonnie Friehling

  Member

  SSRP Certified

  Hi, Mitch,

  How long does the patient have to take off after using MK677 for 90 days, before restarting?

  Thanks

  Bonnie

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