ARA 290

[Caroline Snelwar]

I have a patient with Adhesive Arachnoiditis  who has had success with BPC/ KPV,  and would like to start ARA 290 which I think, from what I am reading would stimulate nerve fiber regrowth with associated improvements in pain and other sensory symptoms, and autonomic function per cited study below.

They used ARA 290 4mg SQ daily for 12 weeks.. is this the standard dosing?

I appreciate any feedback, thank you!

Dahan A, Dunne A, Swartjes M, Proto PL, Heij L, Vogels O, van Velzen M, Sarton E, Niesters M, Tannemaat MR, Cerami A, Brines M. ARA 290 improves symptoms in patients with sarcoidosis-associated small nerve fiber loss and increases corneal nerve fiber density. Mol Med. 2013 Nov 8;19(1):334-45. doi: 10.2119/molmed.2013.00122. Erratum in: Mol Med. 2016 Oct 20;22:674. PMID: 24136731; PMCID: PMC3883966.

[Kristelle Reyes]

Hello @cab45cgmail-com,

Here are the other discussion boards that might help you:
https://ssrpinstitute.org/srrp-discussion-board/topic/ara-290/
https://ssrpinstitute.org/srrp-discussion-board/topic/ara290/
https://ssrpinstitute.org/srrp-discussion-board/topic/arachnoiditis-and-crps-and-peptide-optimization/

I’m also looping in @byurthgmail-com, @cpaigepaigemd-com, and @drhusaininterlinkedmd-com, we would love to have your insights here. Thank you! 🙂

[Abid Husain]

I would also consider GHK-Cu.  There is data to show it has been useful in promoting new nerve growth.  It has been used for treatment in neuropathic pain and anxiety.

Here are some summary papers on it’s overall effects.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332963/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/

 

[Caroline Snelwar]

Thank you very much, I will keep you posted on her progress!

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