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Cause of high testosterone in 84 yr old female

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Cause of high testosterone in 84 yr old female

Rita Ferraro, ND July 27, 2021 at 7:48 pm

6 Replies

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  • #30883
    Rita Ferraro, ND
    Member
    SSRP Certified

    Can ruptured silicone implants used many years ago cause high testosterone in women. I have a patient, 84 yrs old with high testosterone. She is on no meds, looked at all her supplements… maybe I’m missing something. Has no partner she comes in contact with. History of breast cancer and lymphoma. Cleared of lymphoma 1 year ago. Never had chemo, radiation , just surgery. She isn’t on bio identical hormones either.  Any way to get testosterone down? This patient is wary of hormones since she has googled  how estriol can cause breast cancer. I treat the ruptured silicone implants in an ozone bath. You can see the silicone ooze out in the water. It is very effective. 

    #30884
    Kristelle Reyes
    Member
    SSRP Staff

    Hello @drerikaeshealth-com, @cpaigepaigemd-com and @byurthgmail-com, would love to have your insights here.

    Thank you! 🙂

    #30885
    Elizabeth Yurth
    Member
    SSRP Certified

    Interesting study regarding high testostoerne in elderly women. Unless she is having significant issues -not sure would try and lower . Likley offers an advantage

    They looked at women aged 80 to 84 years and found they had testosterone levels that were on average 9.3% higher vs. women aged 70 to 74 years; that percentage rose to 11.3% for women aged at least 85 years (P = .02). Older women with overweight and obesity had higher testosterone levels vs. women with normal weight.

    Researchers also found that, compared with women aged 70 to 74 years, SHBG levels were on average 5.6% higher among women aged 75 to 79 years, 13.6% higher in women aged 80 to 84 years and 22.7% higher in women aged at least 85 years (P < .001 for all). Obesity, however, was associated with a 27% lower SHBG level (P < .001).

    “The increasing proportion of women with unmeasurable [estradiol] in the older groups most likely reflects different effects of age on the enzymatic pathways essential for the biosynthesis of these hormones,” the researchers wrote. “Regardless, a key message from the findings is that studies investigating the association between estrogens and diseases of aging in postmenopausal women must measure [estrone] in order to provide meaningful findings.”

    The researchers noted that that the high androgen levels observed in some women in the cohort reaffirm the “wide range of normality” within a community-based population and support the representativeness of the study sample.

    “The study suggests that higher testosterone may confer a survival advantage, particularly considering that between the ages of 70 to 95 years, older women have higher testosterone levels in this age group,”

    https://academic.oup.com/jcem/advance-article-abstract/doi/10.1210/jc.2019-00743/5548913?redirectedFrom=fulltext

     

    But I will always bow to the expertise of famed hormone guru @drerikaeshealth-com if I am wrong!

    EY

     

    #30887
    Eric Fete
    Member
    SSRP Certified

    I agree in that there is no harm in having a higher testosterone level.  What were her levels?  What were her other labs?  More importantly how does she feel?  In my hormone practice I discuss this with my patients all the time:  how they feel is much more important than the numbers.  Some patients need higher numbers to alleviate symptoms and signs than others.

    Eric

     

    #30888
    Abid Husain
    Participant
    SSRP Certified

    I agree as well. There would be no harm, and probably a protective effect in manmy systems with having a naturally high testosterone serum level.  Is it the total that is only high?  If the SHBG is elevated, that may put her free T into a “normal” range.

    Hope that helps,

    Abid

    #30889
    Kristelle Reyes
    Member
    SSRP Staff

    Claim your CME here: https://earnc.me/O881y4

    #30890
    Rita Ferraro, ND
    Member
    SSRP Certified

    Sorry to thank everyone now but I didn’t see this feedback till now. I did research and came to the same conclusion as everyone above. Thank you Betsy, Abid and Eric. I shared the information with my patient and she was relieved.

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