Desmond tumor

[Rita Ferraro, ND]

Female patient over 50 has a desmoid tumor above heart and has infiltrated her left breast. She was told by an oncologist in Albuquerque to have a mastectomy. She refused this in February and went to the Mayo Clinic for a second opinion. They told her: “As the tumor is growing fast, the recommendation by the multidisciplinary team is to proceed with chemotherapy. We will see how you respond to treatment after 3 cycles and reevaluate. Generally desmoid pts live for years as it is a benign condition. Once again, I want to make sure I say it, anti hormone therapy is effective in only 1 in 4-1 in 5 patients, so please think about it before wanting to move forward with that option”.

I know we have talked about fibrosis and will be getting into it more in Malibu. A functional medicine approach for treatment would be appreciated. Time is of the essence. Thank you all in advance. I don’t know the chemotherapy drug they want to use.
Rita

[Kristelle Reyes]

Hello @drhusaininterlinkedmd-com and @cpaigepaigemd-com, would love to have your insights here. Thank you!

[Rita Ferraro, ND]

I have begun to use 3-bromopyruvate as an MTOR inhibitor. I have experience with 3-BrP. I know rapamycin is also an MTOR inhibitor. May combine the two actually. Started her on TA-1 from a trusted source in Israel and KPV. There is literature and clinical studies using both 3-BrP and rapamycin so I know I am on the right track. Patient is vegan and is staying vegan. We made adjustments in her diet. She has a good exercise routine and lives in the high desert mountains with very good air and access to trails. She will absolutely not do chemotherapy as prescribed by the Mayo clinic in Phoenix. I found a trial where low power HIFU is used to shrink the tumor and the Rochester based Mayo is familiar with it.  Since her tumor is large it would have to be done several times. She reports some shrinkage already but I need to see her. She is on low dose naltrexone 4.5 mgs. I took in consideration the role of the Circadian Clock especially in tumor growth and remembered it regulates one metabolic pathway, insulin, IGF1,P13K,mTOR signaling. If disrupted can accelerate tumor growth. We discussed her sleeping habits and have made adjustments. Patient is on butyrate, Curcumin.  No glutathione as tumors hijack the mitochondria . Glycine in the mitochondria can be converted to glutathione which would fuel the tumor. Could ketone esters at night play a role here? Nobiletin?

SHE IS USING INFRARED SAUNA WHICH HELPS THE FOLDING AND UNFOLDING OF PROTEINS AND ACTIVATES MITOCHONDRIAL BIOGENESIS THROUGH OXIDATIVE PHOSPHORYLATION. SIX DAYS A WEEK…OFF 1 DAY FOR NOW.

Now they want her on tamoxifen. She refused.

I have to make a correction. The tumor is above her heart attached to the chest wall and migrated to her right breast. I saw the x rays and it is large.

[Kristelle Reyes]

Hello @saveyourlife1956gmail-com,

Here’s a video response from Dr. Seeds’ SSRP Office Hours 8/9/22 at 03:29, please watch below:

 

Thank you! 🙂

[Author]

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