HORMONE F.A.Q’s!

[Abid Husain]

WOW!  Love this discussion!  So many brilliant practitioners chiming in.  This a great one to learn from!

I also use oral Estradiol  and Progesterone.  The data I have seen speaks to is safety over any of the synthetic preparations.  It has more reliable delivery and serum levels.  When it comes to testosterone for women, I initially use DHEA as women have better conversion of it to testosterone.  If that is not effective then testosterone topically, since the dose requirement for women is much lower.

I am not a fan of pellets in general.  I dont feel it mimics physiologic delivery in any way.  Testosterone release has a circadian rhythm, like every other hormone and a large bolus dose wont mimic that.  My understanding is that optimal dosing would mimic daily patterns, so daily high concentration cream or low dose daily SQ shots.  Mext best option is mid range dose every 4 days, if using cypionate.

I would love to read any data to make me rethink my approach.

Thanks everyone!

Abid

[Eric Fete]

Hey Abid

Thanks for the post- we have a lot in common – we met at the first Mastermind 3.  I would love to connect.  Give me a call  or shoot me your #.  740-704-5386

Eric

[Amanda Myres]

Thank you all for such excellent info!! Any thoughts on sublingual troches  for testosterone? Or estradiol for that matter?
Betsy, Suzanne, and Erika- I listened to your podcast with Nathalie regarding hormones, it was fabulous and I hope you do more together!

[Erika Schwartz]

I have problem with oral absorption of testosterone and estradiol and their metabolism through the liver.

I find that oral estradiol converts to estrone and increases estrone levels very quickly with unknown and potentially undesirable effects.
Testosterone doesn’t really get absorbed orally and the blood levels stay low while LFTs go up.

Hope this helps. Sending everyone lots of sunshine and peace!

Erika

[Elizabeth Yurth]

Thank you @visanawellnessmdgmail-com!!

I have to agree with @drerikaeshealth-com on not using any hormones except progesterone as oral! Liver toxicity is high.  And beyond what Dr E says ( and she is the true expert here) about the negative metabolism… oral estrogens increase blood clot risk, transdermal does not!  Would rec stay in the better safe zone using TD T and E and only use progesterone oral.

EY

[beth panoff]

I’d love to hear everyone’s thoughts on hormone testing… serum , saliva or urine and why they chose either modality for assessing hormones and monitoring bhrt.

thanks!

[Harriet McCoy]

Does anyone know which lab does  hormone fingerstick blodspot testing?

[beth panoff]

ZRT does a dried blood spot from a finger stick

[Harriet McCoy]

Thank you!

 

[Mona Ehasz]

Hi everyone!

Say I have a new female patient (53 yo) who’s on existing transdermal estradiol/testosterone and PO progesterone. Besides lifestyle modifications (diet, gut health, stress management, etc) I want to tune her up with peptides along with hormones. How do I go about it? Adding GHRH/GHRP? DSIP? Kisspeptin?

What about her current BHRT dosing? Should I turn them down a little bit since she’s going to get a boost from the peptides? How much adjustments?

Much appreciated! I’m a new SSRP member and have been watching all the masterminds videos daily to catch up, this cellular medicine is so amazing!

 

Thank you

Mona

[Abid Husain]

Hello Mona,

Welcome to the SSRP!

I do not need to reduce doses of BHRT when using GHRH/GHRP peptides.  They will have a great added benefit but will not directly affect their hormone needs.  That being said, if you are reducing cell senescence and improving cell efficiency it is a good policy to continue to monitor clinical status and lab markers for changes.

When using DSIP, Kisspeptin or Gonadorelin it is important to keep the BHRT dosing in mind.  Since DSIP and Kisspeptin will stimulate the LH receptors you will want to consider that per patient.  Individual responses vary so a set protocol is difficult to apply.  My recommendation is to start  the peptides and monitor clinical responses and periodic labs.  Gonadorelin is GnRH and will stimulate LH and FSH release so same type of process applies.

I dont recommend reducing doses in anticipation of the peptide responses.  If they are already doing well with the current BHRT, I wouldn’t change that and I would add GHRH / GHRP’s.  They will have a great response and it will be the best overall bang for the buck.  If there are sleep issues, DSIP will be a good multi-use peptide to help sleep and LH stimulation ( and on the topic of sleep, GHRH/GHRP will help that too).

At 53, I don’t think that kisspeptin or gonadorelin would be of great utility as the ovaries are probably low in function and wont do much with more stimulation.

I hope this helps,

Abid

[Mona Ehasz]

Thank you so much Abid! Hope to see a lot of the folks here on September 10 – 11 in Las Vegas!

[Kristelle Reyes]

Hello everyone!

Claim your CME here: https://earnc.me/bY6Nq6

[beth panoff]

Does anyone do estradiol compounded in oil to avoid the first pass effect and still have the benefits of oral E2? The integrative physician I used to work with always compounded oral in oil.
Curious

thank you!

[Caroline Snelwar]

Thank you for a great discussion, and information.

What dosing are you using for IM testosterone in women?

Thank you

[Author]

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