Narcolepsy

[Patricia Salvitti]

It is known that:

Hcrt-1 and Hcrt-2 peptides are undetectable in brain tissue of narcoleptic patients, and that narcoleptic patients exhibit an 85–100% loss of Hcrt neurons compared to control patients

https://www.sciencedirect.com/science/article/pii/S2590098620300579

Rather than a targeted peptide for narcolepsy or excessive daytime sleepiness, anybody have experience with peptides that support the hypothalamus in general and those conditions?

 

[Geoff Jones]

I have narcolepsy.  Have trialed many peptides such as DSIP, epithalon, thymulin as well as using CJC/Ipa, TA1, BPC.  The things that seem to make the biggest difference for me include Xyrem, and Prodrome Neuro in the AM and Prodrome Glia at bedtime (I use 4 caps of each).  I find narcolepsy patients to be quite variable in what they respond to.  Overall, the best results I’ve seen are combining Xyrem and Armodafinil.

[Patricia Salvitti]

Appreciate you sharing your experience.

I’m currently taking Prodrome Neuro and Glia which have helped, and now have a script for a sleep study and MSLT.  I’ve put off doing the studies for many years because the medical solutions appeared to be just a bandaid.

Will be looking into Xyrem and Armodafinil.  Would be nice to stay awake, instead of falling asleep anytime I sit for any length of time!

[Author]

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