NO and Peroxynitrate and Resveratrol

[Eric Fete]

Hello!

NO supplementation (like the capsules that Berekely Life had at the conference)- we know of the benefits of optimizing NO but I have read some studies discussing that too much NO can increase peroxynitrate with all of its attendant adverse effects.  I wanted to see if anyone had data or thoughts on this?

Also what about any new data on Resveratrol and exercise?  If taken pre-workout will it mitigate the effects of training?  Some studies said yes but others later said no.   Dr. Seeds or anyone:  would love input on this!

Eric

[Robin Rose]

Great question. I’ve hobnobbed quite alot with Beth Shirley pharmD the nitric oxide Queen who contributed to deciding the recipe for that product. Yes it can. Always hormesis: in my work with early CKD – it’s clear that CKD is a NO-deficiency syndrome, clinician astute: recognizing the pathology and matching to every strategy to enhance it in a condition of vascular compromise like CKD. Beth’s product comes with saliva dip sticks – anyone know how efficacious??- using these I have seen people improve from low low undetectable to  optimal – she talks about dosing to the case at hand. Some pts only need beets and arugula, in CKD though- clinical assumption is a wise stance. And NOX is a scary threat in the inflammatory nature of this syndrome. Beth would come do a talk for us – she’s a whiz kid !! Eager to hear others’ thoughts

[Kristelle Reyes]

Hello @drkriswyahoo-com and @leonard-pastranagmail-com , would love to have your insights here. Thank you! 🙂

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