Peyronie’s disease

[John Tang]

Does anyone have some advice on how to treat Peyronie’s disease?

Pt has quite severe case and is being treated with Urologist with some traditional Collagenase treatments to break up scar tissue.  Urologist says there is some genetic predisposition.  He denies any autoimmune connection.

Pt’s problem list:

DM Type 1 on Long acting and regular insulin – Hb 1AC 6 -not fully optimized – working on improving

CRI – Cr 1.48  – Can Pentosan Polysulfate be helpful here?

Elevated LDL Particles, LDL

Heavy metals high with Mercury and Lead

Thyroid borderline low – no current symptoms

Severe food allergies including gluten and dairy – he’s avoiding as much as possible

[Bruce Sloane]

Hello-Urologist here. Severe Peyronie’s is very difficult to treat as opposed to mild Peyronie’s which is much more amenable to conservative therapies such as PRP and stretching devices. Dr. Seeds had once posted something about using peptides on the International Peptide Society website using TB-4.  From my perspective, severe Peyronie’s likely needs surgical correction by a urologist experienced with this type of surgery. If the patient is having pain, LISWT (ie Gainswave) can reduce the pain but will not correct the curvature.

Hope that helps.

Bruce Sloane MD

[Kristelle Reyes]

Thank you for that great input @bbsloanecomcast-net! 🙂

Would love to have your insights here as well, @drkriswyahoo-com and @byurthgmail-com. Thank you! 🙂

[Kris Wusterhausen]

Hello! I have had good look with using a shockwave treatment focused on the scarring causing the Peyronie’s. After the shockwave treatment, I think inject PRP into the actual scar. you will most likely want to do a block because injecting into the scar is more painful than normal. I would then repeat this process q 4 to 6 weeks for up to 3 cycles. If this does not help/correct the issue then off to the urologist we go for a possible surgical intervention. I have personally seen curvature with shockwave when combined with PRP at same visit. We do use a different shockwave tip and settings for this procedure vs normal ED shockwave treatments.

I hope this helps

Kris

[Kristelle Reyes]

Claim your CME here: https://earnc.me/VaOVwE

[Author]

Posts