Post covid

[Michele Zormeier]

I have a 53 yo patient with painful swollen joints knees shoulder ankles. She had covid in December treated with ivermectin hydroxychloroquine orthomune silver Hydrosol transfer factor, did ok. Then shortly thereafter began with painful swollen knees then ankles now shoulders. On Genova testing she has minimal food sensitivities with over growth of partially pathogenic bacteria. She is on metagenics supplements for GI and detox program metagenics, gluten dairy free. Peptides ordered BPC/KPV orally , TA1 25 U bid, LDN
do you have other recommendations ?  Would you add TB4? Or LL37?

I would appreciate any suggestions you would have.
thank you so much

[Carl Paige, MD]

Has she had any labs for autoimmune process.  Thyroid antibodies, ANA and secondary antibodies for autoimmune conversion after covid (not uncommon).   At least add back quercetin and SPM   https://17fwxf1trr45xut7r3i2d4ya-wpengine.netdna-ssl.com/wp-content/uploads/2018/06/TimesStyleArticleREVISEDv6_2018.pdf

Lab interpretation: https://test.mayocliniclabs.com/it-mmfiles/Autoimmune_Disease_Testing_Algorithm.pdf

lab example:  https://testdirectory.questdiagnostics.com/test/test-detail/36378/analyzer-ana-ifa-with-reflex-titerpattern-systemic-autoimmune-panel-1?p=r&q=Autoimmune%20Ana&cc=MASTER

Covid/autoimmune:  https://pubmed.ncbi.nlm.nih.gov/33332890/

May consider adding back hydroxychloroquine if positive autoimmune panel.  I also follow endothelial dysfunction parameters, MPO, LP-PLA2, Fibrinogen Ag and if + use  Nattokinase

Natural fibrinolytic:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372539/

Thinks of post covid as a systemic autoimmune dysregulation chronic inflammatory syndrome, CIRS etc.     If unilateral edema evaluate for thrombosis .

For peptides:  yes if fibrosis markers present TB4 https://pubmed.ncbi.nlm.nih.gov/?term=Thymosin%20beta%204%20fibrosis

melanotan II  https://pubmed.ncbi.nlm.nih.gov/?term=Melanocyte+stimulating+hormone+anti+inflammatory

Hope that gives you some other things to work with

 

Carl

[Michele Zormeier]

Thank you

auto immune panel negative So far. Some labs Still pending

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