Use of peptides in adult Hypophosphatasia

[Kenton Crowley]

Hi Group, I have a 57yo German female with hypophosphatasia and wonder if anyone has experience using anything other than asfotase alfa for treatment?

[Kristelle Reyes]

@byurthgmail-com @drhusaininterlinkedmd-com Hello doctors, any thoughts on this?

[Elizabeth Yurth]

How low is the alk phos?? In general, low alk phos in adults is due to some other underlying issue-biliary, liver? I am sure you made sure D is optimized as well.  If no underlying issues and remainder of the labs are OK, , there is some question in the literature whether there is truly much harm. SO make sure you have dug for etiologies. If still concerned, could try TA1 and a course of ursodiol or tudca.

Dr Yurth

[Kristelle Reyes]

@drkentpccorp-org

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