[Aaron Hartman]

Thanks for that.

[Aaron Hartman]

Alyx,

I have done a lot with my 17 year old daughter and other patients with varying degrees of CP. At her age, I’d focus 1st on lipid therapy including some advanced lipid membrane testing. HBOT also can be super helpful to stop ongoing neural inflammation, if the family has the money for HBOT. Low pressure HBOT at 1.3ATM also has literature on it (even as low at 1.15ATM in alzheimer animal models).

Obviously all the gut stuff as well, with a brain injury in utero, the child will have gut issues.

On the peptide part, Cerebrolysin can be good. I give it to my daughter twice weekly IM but I had to order it from Austria and have it sent directly to my office.

Thymulin would be useful to abait the neural inflammation and Intense PT can be super helpful. NMS, PowerDot or other forms of stimiluation will abate the spasticity over time as well.

 

Hope this helps

Aaron

[Aaron Hartman]

Thanks for the detailed thoughtful responses.

[Aaron Hartman]

Abid,

I agree with you, just wondering if the training that Dr. Seeds led there, counts in this forum at all?

I’m doing the Brain summit currently and it’s great info but also wondering if any of my previous training ‘counts’  in this ecosystem.

Aaron

[Aaron Hartman]

Madison,

Thanks for that data filled response.

My clinical research company, Virginia Research Center, did some of the initial studies with GLP-1’s almost 10 years ago and we’ve been involved with research on them since as a primary prevention for acute coronary syndromes as well as weight loss. I’ve used it in my Type I patients with great success. I use it primarily to decrease their insulin usage (due to how bad long term insulin usage can be) and in a few who followed a strict diet, I was able to get them back to physiologic insulin dosages (for example one patient was on 50 Units daily and got him down to 10).

Aaron

[Aaron Hartman]

Has anyone tried systemic therapy (like TA-1/TB-4) to see if that has any + effect on the plaques?

 

[Aaron Hartman]

Thanks for this exhaustive and complete response. It is super helpful and encouraging.

Aaron

[Aaron Hartman]

Thanks for the input. I’ll discuss options with him at follow up.

[Aaron Hartman]

Carl,

Thanks for the detailed response. Didn’t think about kisspeptin so that is an interesting option in low LH patients. I did get my LH backwards in regards to clomid, thanks for the gentle reminder

Aaron

[Aaron Hartman]

Thanks or that input

[Aaron Hartman]

Robin,

Could you clarify what you mean? Before coming into SSRP I had only used Elmiron for IC. Now I’m looking into SC for OA and other indications. What kinds of complications and issues have you had with its use and via what modes of administration?

Thanks

Aaron

[Aaron Hartman]

Thanks.

Would a subjective way to figure this out be to titrate up Relora until it causes sedation? then cut it back? Relora is significantly cheaper that DHH-B and the ones I recommend this to are already on other peptides.

Aaron

[Aaron Hartman]

Dr. Fleisher,

Thanks for that. Looks like I need to start using LL-37, havn’t done any trial with it to date.

Aaron

[Aaron Hartman]

Sounds good, I’ll try those and see if the reaction stops flaring.

[Aaron Hartman]

Very helpful.

Thanks for the insight. Could this logic be applied to TB-4, where it is used ‘continuously’ during M-F but off on weekends? since in effect over a 3 month time frame the patient would be off 30 days out of 90?  This actually might help with compliance and keeping protocols more similar.

Aaron

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