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Consider DUTCH test …. See how he is metabolizing hormones. Then make the needed adjustments
from above … agree increasing the dose to get symptom relief.
if keto have him cycle or target keto ….
They will begin to ovulate once insulin resistance reverses….. sometimes the ovaries are very sensitive and / or resistant to insulin.
as well peripheral conversion of estrogen can decrease with weight loss and body composition changes.
all of the above will have an impact on ovulation and cycle change.
in the vein, if someone does not want to become pregnancies that need to be addressed while on these meds.
hope that helps
Leonard that is such great new for Oklahoma!!!!!!!!! Thank you for the information!!
I would recommend using a dermal estradiol – femring 0.5 mg is a nice place to start if she has the Dexter to place it in the vagina, she gets all the systemic benefits plus the general urinary. As well there’s no liver issues going on because it’s already active before first past metabolism. I agree I would use micronize progesterone 100 to 200 mg at HS to help enhance the impact with out worrying about the breast tissue. You could even use a little bit of testosterone with her for more vitality. Reduce her brain fog 25 mg. IM o 3 to 4 weeks. Always start with a heart scan and see what a calcium burden is. Make sure she’s doing some intermittent fasting to make sure she’s got some good insulin sensitivity which is always very important for these women as they’re getting older. Not a fan of oral estrogen and see if it’s estradiol cause they still do not absorb very well compared to the dermal.
Thank you so much!! Appreciate it!!!
How long can BPC at high doses be used… life long or drop down for maintenance. She feels better at higher dose of BPC but have only gone 300 bid. Pentosan sSQ or IM, feel like at the cert course it was stated works better with deeper injection???
Thank so much!!
December 27, 2022 at 5:21 pm in reply to: Can a patient use hcg & kisspeptin instead of hcg and clomiphene for fertility purposes? #32223yes, monitor ovaries with ultrasound for hyperstimulation and see her response plus measure the lining of uterus to make sure it is responding with at least 8 mm thickness.
December 21, 2022 at 10:02 am in reply to: Can a patient use hcg & kisspeptin instead of hcg and clomiphene for fertility purposes? #32221I just used with an older patient with clomid, I did 200 mcg on day 2 and day 5-9 of clomid and then again 300 mcg with follicle size of 1.5 cm for oocyte maturation. No protocol, this was based on my thoughts as GnRH and 20 years of ob/gyn practice… Waiting for results of hopeful positive pregnancy test in about 10 days… I did not find much out there and Dr Seeds mentioned some fertility upcoming protocols…
Can Pentosan be used long term, and subcutaneous is fine?? ( she has been on celebrex 200 bid for 12 years… )
Thanks for teaching and help!! I”ll let you know who she is doing in about 6 months!!
Hello Jamie,
Sorry it has been a hot minute! I have been able to review her report and they do not have SOD1/2. However I do have the other results: CAT CC, GPX1 CT, FOXO3 TT, SIRT1 TT.
I am just starting my jump into peptides and this may be a stupid question.. is there a peptide to add to the above supplements that would be helpful to reduce her oxidative stress and inflammation. Fatigue and body aches are the main. She has no insulin resistance issues, normal BMI, and I am working to optimize her hormones (mid-40’s). PS I am a practicing gynecologist…
Thanks for the help really appreciate it!!!
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