This course introduces a cellular medicine framework for understanding how cells make energy and adapt to stress through changes in metabolism, mitochondrial function, redox balance, and signaling that influences gene expression. Across six lessons, you will examine how common stressors contribute to cumulative burden (“allostatic load”), how cells shift between glycolysis and mitochondrial respiration, and how oxidative stress can shape downstream responses such as repair, autophagy, senescence, or apoptosis. The course also connects immune activation to energy and cofactor demands, and uses epigenetic “signatures” to illustrate how phenotype can shift without changing DNA sequence. Clinicians can use these concepts to support clearer mechanistic reasoning, interpret physiology-informed testing more cautiously (for example, understanding why methylation results may be limited without pathway context), and organize complex presentations into a stepwise framework. It is designed for health professionals and advanced students who want a structured foundation for thinking at the cellular level and following patient response over time with measurable clinical and laboratory endpoints where appropriate.

The course is organized as six on-demand lessons that build from foundational cellular concepts to applied mechanistic frameworks. The sequence is designed to help you connect stress, energy metabolism, and signaling to clinically relevant patterns without relying on protocol-driven instruction.

• Over 1 hour of video content
• 3 modules
• 6 video lessons
• Downloadable learning guides