MOTS-C dosing

[Biana Borchenko]

I am new to MOTS-C peptide. Have been using NAD for a few years but now would like to incorporate MOTS-C. What is a good dosing protocol? I read that anywhere between 2-10 mg three times a week is used.

[Renee Pacella]

Hello!

Dr. Seeds addresses this exact topic in the latest episode of Dissecting Protocols. Be sure to check out the video when you get a chance—and feel free to reach out if you’d like to discuss further!

Dissecting Protocols – July 2025

Incorporating MOTS-c with NAD

Dr. Seeds breaks down the molecular strategies behind improving metabolic flexibility using MOTS-c and a deeper understanding of NAD salvage pathways. Learn why substrate switching is key for energy efficiency, and how precise interventions—like small molecule NNMT inhibitors—can reshape redox balance and mitochondrial resilience. Whether you’re treating aging, fatigue, insulin resistance, or mitochondrial dysfunction, this is essential education for anyone interested in precision cellular medicine.

[dr.jcruzgonzalez@gmail.com]

Has anyone found a reliable source for MOTS-c recently? I checked with Brooksville and they don’t have it at the moment. Curious where you are currently sourcing it from.

[Author]

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