Mastermind 15 – The Aesthetic Matrix

LIVE
Masterminds
2.5-Day Event
Mastermind 15 - Live
Ko Olina, Oahu Hawaii
March 13–15, 2026
Regular Price $2,295
Pro Members $1,795
Register Now
Virtual
Masterminds
2-Day Virtual Event
Mastermind 15 - Virtual
Virtual Summit
April 3–4, 2026
Regular Price $995
Pro Members $895
Fellows $749
Register Now

Cellular Medicine Mastermind

Redox and Mitochondrial Medicine for Total Skin, Hair, and Body Rejuvenation

MASTER THE LATEST CELLULAR MEDICINE THERAPIES YIELDING TRANSFORMATIVE AESTHETIC RESULTS

The future of aesthetics extends beyond superficial skin treatments. Mastermind 15 presents Cellular Medicine as an emerging science-based approach for creating true skin and body rejuvenation from within. The cellular engines that produce authentic aesthetic results (including mitochondrial health, redox signaling, and regenerative immune responses) will provide practitioners with a strong new framework to enhance their results and increase patient satisfaction while aging gracefully.

You will learn how to utilize biological processes to restore fibroblast, melanocyte, and keratinocyte function, enhance skin texture and tone internally, reverse hair loss at the follicular level, and reshape the body through metabolic signaling (instead of devices). You’ll learn to implement advanced protocols with peptides, exosomes, stem cells, and redox therapies to deliver deep and enduring results.

Event

What's Included

Join us live or tune in to our virtual summit

In-Person

  • 2.5 day in-person experience
  • Full Event Refreshment Package
  • Friday Sunset Reception: networking, drinks, dinner
  • 20 hours of content > 8 immersive modules > 32 lessons
  • Virtual Summit access, including group Q&A with Dr. Seeds
  • Lifetime on-Demand access to recordings, slides, and lesson guides
  • CME add-on option*
  • SSRP Group Discount Rate at the Four Seasons Ko Olina Hotel**

* – $200 add-on fee** – while supplies last

Virtual Summit

  • 2 day virtual experience
  • 20 hours of content > 8 immersive modules > 32 lessons
  • Virtual group Q&A with Dr. Seeds
  • Lifetime on-Demand access to recordings, slides, and lesson guides
  • CME add-on option*

* – $200 add-on fee

The Mastermind Virtual Summit is built for clinicians who want the depth, rigor, and peer engagement of the Mastermind—but cannot step away from their practice. Rather than passive, on-demand viewing, the Virtual Summit provides scheduled, protected learning time with live participation, real-time Q&A, and structured discussion alongside fellow SSRP Members.

Sessions are followed by dedicated Q&A with Dr. Seeds, addressing the most clinically relevant questions. Hosted just weeks after the in-person event, the Virtual Summit delivers a digital experience unlike a standard livestream —professionally produced, academically grounded, and fully supported by the SSRP Team to ensure a seamless learning experience.

Questions? Our Provider Care Team is here to help.

Questions? Our Provider Care Team is here to help.

We'd love to help you determine the best next steps on your Cellular Medicine journey.

Mastermind 15 - The Aesthetic Matrix Live Event Agenda (HST)

Venue Title Speakers Time
Ko Olina, Oahu Hawaii THE BIOLOGY OF BEAUTY
Mitochondria, Redox Signaling, and the Foundations of Skin Health.
  • The origin of aging cells from cellular energy consumption and redox balance.
  • The role of ROS in regeneration has been widely misunderstood in scientific literature.
  • Sirtuins activate mitochondrial signals while NAD⁺ acts as a signaling molecule for dermal layers.
  • The Cellular Medicine perspective presents a new perspective on oxidative stress.
William Seeds, MD
William Seeds, MD
8:00 AM - 10:00 AM
Ko Olina, Oahu Hawaii AESTHETIC CELL ATLAS
Fibroblasts, Melanocytes, Keratinocytes, and Immune Crosstalk
  • The process of collagen remodeling and bioenergetics depends on fibroblasts.
  • The melanocyte regulatory system functions as a pigment optimization mechanism.
  • Keratinocytes perform barrier renewal and inflammatory signaling through their turnover process.
  • The immune system consists of mast cells and Langerhans cells that work with chronic aesthetic inflammation.
William Seeds, MD
William Seeds, MD
10:30 AM - 12:30 PM
Ko Olina, Oahu Hawaii REJUVENATION PATHWAYS
The Skin's Regulatory Network consists of AMPK, mTOR, FOXO, NRF2 and various other signaling pathways.
  • The energy sensors along with protein turnover regulators function as the main control mechanisms.
  • Autophagy and mitophagy enable the skin and hair to achieve optimal health.
  • The NRF2–KEAP1 axis operates as a defense mechanism against UV light and an antioxidant response system.
  • The pathogenesis of aging occurs due to imbalanced pathways which health care providers fail to understand in their upstream mechanisms.
William Seeds, MD
William Seeds, MD
1:30 PM - 3:30 PM
Ko Olina, Oahu Hawaii EXTERNAL EXPRESSION
Gut, Hormones and Metabolic Dysregulation create skin and hair effects.
  • Estrogen and testosterone along with thyroid hormones and cortisol serve as hormonal signals that affect the body.
  • The gut–skin–immune axis functions as a system which combines endotoxins with microbiota to create skin reactivity.
  • The combination of insulin resistance with glycation creates dermal inflammation.
  • The skin shows signs of mitochondrial adaptation during systemic illness.
William Seeds, MD
William Seeds, MD
4:00 PM - 6:00 PM
Venue Title Speakers Time
Ko Olina, Oahu Hawaii REGENERATIVE TOOLKIT
Peptides, Exosomes, Stem Cells and Future-Ready Biologics
  • GHK-Cu, BPC-157, TB-4, Epitalon & more ,mechanisms together with their clinical applications.
  • Exosomes , stem cells and mitochondrial EVs and their roles in skin healing processes.
  • Future biologic innovations through Klotho and FOXO modulators and SIRT activators.
  • The differences between systemic and local intervention strategies.
William Seeds, MD
William Seeds, MD
8:00 AM - 10:00 AM
Ko Olina, Oahu Hawaii HAIR REGENERATION
The Follicle as a Metabolic Sensor
  • How HFSCs manage their mitochondria during hair growth cycles.
  • How prostaglandins together with androgens and inflammatory mediators affect the body.
  • Cellular disruptions in alopecia by identifying root causes and describing reprogramming strategies.
  • How to combine peptides with redox and hormones in treatment protocols.
William Seeds, MD
William Seeds, MD
10:30 AM - 12:30 PM
Ko Olina, Oahu Hawaii WHOLE-BODY INTEGRATION
Fat, Muscle, Skin, Fascia, and the Lymphatic Interface
  • The bioenergetic processes that occur during fat remodeling and browning.
  • Muscle tone functions as an aesthetic signal through myokines.
  • Skin elasticity and fascia as structural elements that people tend to overlook.
  • Mitochondrial drainage functions through lymphatic flow to create both tone and clarity.
William Seeds, MD
William Seeds, MD
1:30 PM - 3:30 PM
Ko Olina, Oahu Hawaii Clinical Care
Case Studies, Systems-Based Assessment, and Implementation
  • Clinical phenotype mapping and upstream targeting
  • Patient stratification and outcome-driven protocol design
  • The walkthroughs of cases include aging face, melasma, post-procedure, acne
  • Redox, peptides, hormones, and metabolic restoration are integrated in the treatment.
William Seeds, MD
William Seeds, MD
4:00 PM - 6:00 PM
Venue Title Speakers Time
Ko Olina, Oahu Hawaii Overflow
Additional time scheduled for audience questions, deep dives, and remaining material from previous days.
William Seeds, MD
William Seeds, MD
8:00 AM - 12:00 PM

CME Credits

Eligible for AMA PRA Category 1 Credits™

This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the co-sponsorship of Northeast Ohio Medical University and Seeds Scientific Research and Performance Institute. Northeast Ohio Medical University is accredited by the ACCME to provide continuing education for physicians. Northeast Ohio Medical University designates this live activity and enduring material activity for AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The maximum number of CME credits available will be released closer to the event.

VENUE

FOUR SEASONS OAHU RESORT AT KO OLINA IN OAHU, HAWAII

Venue

Oʻahu is a breathtaking tropical paradise known as “The Gathering Place,” where jagged green cliffs meet sparkling turquoise waters across diverse landscapes—from the legendary surf of the North Shore to the serene sands of Lanikai Beach and lush valleys like Kualoa Ranch. It’s a vibrant mix of urban energy in Honolulu and peaceful natural retreats, offering unforgettable hikes, cultural landmarks, and iconic island scenery.

Nestled on Oʻahu’s sun-kissed leeward coast in Ko Olina, the Four Seasons Resort Oʻahu offers an elegant beachfront retreat with panoramic ocean vistas, infinity pools, lagoons, lush gardens, a luxury spa, and tennis and fitness facilities. Guests enjoy access to water sports, a championship golf course, multiple dining venues, and spacious, refined accommodations—creating a harmonious blend of adventure and relaxation in a prime island setting.

FAQ

Frequently Asked Questions

Is Mastermind eligible for CME credits?

Yes! Registrants are eligible for AMA PRA Category 1 Credits™. The maximum number of credits will be released closer to the event. To claim credits, you must select the add-on option at checkout or at any point thereafter.

This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the co-sponsorship of Northeast Ohio Medical University and Seeds Scientific Research and Performance Institute. Northeast Ohio Medical University is accredited by the ACCME to provide continuing education for physicians.

Northeast Ohio Medical University designates this live activity and enduring material activity for AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Everyone involved in the planning, reviewing and teaching of this activity was required to complete a disclosure form indicating all relevant financial relationships with any ‘commercial interest’. A ‘commercial interest’ is any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on, patients. This is done so that the audience can determine whether an individual’s relationships may influence the presentations. The reviewers and planners of this activity have disclosed there are no relevant financial relationships with any ‘commercial interests’.

What does registration for Mastermind 15 include?

What is the daily agenda for the in-person event?

Is there a group hotel rate?

Which airport should I fly into/out of?

How many attendees can register for Mastermind 15?

What is your refund policy?

I can’t make it in-person. Can I participate remotely?

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  • Everything included in SSRP Digital
  • Cellular Medicine Mondays Video Series
  • Peptide World Congress Recordings Archive
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Unlock our full range of Cellular Medicine provider benefits and resources. Get everything from SSRP Digital as well as access to:

  • Everything included in SSRP Plus
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GET STARTED

Start your Cellular Medicine journey with our Founder and Academic Chairman, Dr. William Seeds, and build a strong foundation in a cellular-level approach to patient care.

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