Resource Library

As AI tools like ChatGPT move into clinics and prescription renewals, Dr. Seeds weighs their real limits against the hype. He argues pattern-matching software cannot interpret changing patient biology or replace mechanistic reasoning, while acknowledging AI can help synthesize histories and structure data when used as a support tool.

Alzheimer's gets reframed as a phenotype rather than a single plaque disease. The discussion breaks down five converging drivers: amyloid and tau from lost proteostasis, microglial neuroinflammation, mitochondrial energy failure, vascular dysfunction, and insulin resistance, all tracing back to oxidative stress in the neuron over decades.

The gut and brain talk constantly. Dr. Seeds walks through how barrier breakdown, low-grade immune activation, and vagus-nerve signaling connect a struggling microbiome to neurodegeneration. Short-chain fatty acids like butyrate, dietary fiber, and metabolite signaling take center stage over simplistic good-versus-bad bug thinking.

Fresh off a review paper published in JAAOS Global Research and Reviews with co-authors Dr. Omar Raman and Dr. Stephen Lee, Dr. Seeds discusses therapeutic peptides in orthopedics. The conversation covers wound-healing agents like BPC-157 and GHK-Cu, growth hormone secretagogues, and the need for rigorous clinical trials.

A single 81 mg aspirin does far more than thin blood. Dr. Seeds explains how acetylation shuts down COX-1 while retasking COX-2 to produce pro-resolving mediators like resolvins and lipoxins from omega-3s, plus its effects on the cGAS-STING pathway, PPAR alpha and the resolution of chronic inflammation, along with who should avoid it.

Red light therapy and cold plunge headline this look at popular rejuvenation tools and where the marketing outruns the science. Dr. Seeds explains how red light sparks the electron transport chain and cytochrome c oxidase to support soft-tissue healing and skin, while cautioning that its effects stay superficial and short-lived.

A back-to-basics look at cellular medicine, told by the innovator behind the framework. Dr. Seeds lays out four pillars: redox balance, mitochondrial signaling, core metabolic pathways, and cellular resilience, then traces how his orthopedic practice revealed that treating the cellular environment, not just the diagnosis, changes patient outcomes.

Sarcopenia takes center stage as Dr. Seeds dismantles the fear that GLP-1 peptides cause muscle loss. Preserving lean mass during weight loss comes down to adequate protein and leucine, resistance training, and slow, deliberate fat loss that lets the body build efficient, mitochondria-rich muscle.

Often overlooked, the lymphatic system drains cellular debris and activates immune defenses through nodes rich in T and B cells. Dr. Seeds explains why lymph flow and the brain's glymphatic drainage are redox-driven, when lymphatic massage genuinely helps, and how stage-four sleep clears amyloid and tau.

Bad breath is often a window into the oral microbiome. Dr. Seeds connects chronic halitosis to dysbiosis, biofilm and plaque, redox imbalance and immune dysregulation in the gums, tracing how these bacteria and their endotoxins contribute to heart disease, neuroinflammation and insulin resistance. Saliva, lactoferrin and flossing emerge as key defenses.