by William Seeds, MD | Aug 6, 2026 | Article
Mitochondrial dysfunction is one of the most firmly established hallmarks of aging, but the field has spent far more energy describing genetic causes of mitochondrial failure—mtDNA mutation, defective OXPHOS, impaired unfolded protein response—than the...
by William Seeds, MD | Jul 14, 2026 | Article
After a recent Journal Club episode in which I featured, The Renin–Angiotensin–Aldosterone System (RAAS): Beyond Cardiovascular Regulation, I wanted to return to the article and expand a bit on the significance of the Renin–Angiotensin–Aldosterone System (RAAS). As we...
by Scott Sherr, MD | Jul 2, 2026 | Article
Scott Sherr, MD | Lucía González Forte, PhD Submitted for publication [Article] to the SSRP Institute Abstract Methylene blue (MB) is a century-old compound whose renewed relevance in clinical medicine reflects a clearer understanding of its role in...
by William Seeds, MD | Jun 3, 2026 | Article
The Overlooked Connection: Dysbiosis and Degenerative Disease Degenerative musculoskeletal diseases, including osteoarthritis (OA), osteoporosis (OP), sarcopenia (SP), and intervertebral disc degeneration (IVDD), affect well over a billion people globally and share...
by William Seeds, MD | May 14, 2026 | Article
In this research article, I return to the subject of my first-ever Journal Club (Ep. 017), in which I discussed a 2023 research study entitled, “Naturally derived cytokine peptides limit virus replication and severe disease during influenza A virus infection”...
by William Seeds, MD | Apr 21, 2026 | Article
Introduction In March of this year, I did a Rabbit Hole (Episode 079) in which I discussed a number of trends marketed to the wider public promising sleep improvement. As you know, a huge swath of the population suffers from sleep disturbance. According to the NIH,...
