Cellular redox and signaling foundations for clearer interpretation of fatigue, inflammation, and metabolic strain
For clinicians seeking a stronger cellular reasoning framework
This course teaches a cellular-medicine framework for understanding how cells manage energy and oxidative stress, with an emphasis on redox balance (NAD/NADH and NADP/NADPH) and key signaling pathways that regulate growth, repair, and recycling (AKT, mTOR, and AMPK). You’ll connect core metabolic pathways—such as glycolysis, the pentose phosphate pathway, and lactate handling—to clinical questions about oxidative burden, nutrient sensing, and stress responses. The curriculum also covers autophagy (cellular recycling), one-carbon metabolism (pathways that support DNA building blocks and methylation), and circadian biology as a practical lens for history-taking and interpretation. Along the way, the course uses applied examples such as interpreting homocysteine with methylmalonic acid and evaluating “hyperbaric oxygen” claims using oxygen partial pressure concepts. The goal is to support clinicians in building clearer mechanistic explanations, improving confidence when reviewing labs, medications, and timing-related factors, and organizing complex cases for follow-up and reassessment over time. It is designed for clinicians and other healthcare professionals, with additional relevance for researchers and advanced students who want a structured way to translate metabolism and signaling concepts into clinical reasoning.
What's Included
The course is delivered as long-form, mechanistic teaching that connects cellular pathways to practical clinical interpretation. Concepts are reinforced through applied discussions and Q&A that emphasize how to organize hypotheses and revisit them with longitudinal follow-up.
- Over 10 hours of video content
- 2 modules
- 8 video lessons
- Downloadable learning guides
William Seeds, MD
Before establishing the SSRP Institute, Dr. Seeds served as a board-certified orthopedic surgeon and sports medicine specialist for nearly three decades, including Chief of Surgery, Orthopedic Residency Site Director, and Director of The Ohio Bone & Joint Institute for University Hospitals.
His significant contributions to sports medicine have been recognized at the NFL Hall of Fame. He has consulted for athletes across all major sports leagues, including the NFL, NHL, MLB, NBA, and even the performers on “Dancing with the Stars.”
Through his research at the SSRP Institute, Dr. Seeds continues to explore the cellular pathways and mechanisms that positively impact disease and dysfunction in the body as well as optimize physical performance.