Mastermind 9: Cellular Medicine

This mastermind course uses the microbiome as a lens through which to deepen your understanding of the metabolic pathways involved in cellular health, and disease. Dr. Seeds offers a careful and in depth exploration of many aspects of microbiome activity, including how tryptophan is “routed” into different biological pathways, and why that matters for gut barrier function, immune balance, and neuroimmune signaling. You will compare the serotonin and melatonin pathway with kynurenine-related metabolites and microbiome-derived indole signals, with emphasis on how inflammation, stress, and dysbiosis can shift this allocation. The course also connects these concepts to circadian timing and introduces practical monitoring considerations, including how clinicians may incorporate a kynurenine:tryptophan ratio while accounting for current limitations in standardization.The goal is to help clinicians organize complex presentations—such as mixed gut, immune, and mood/cognition symptoms—without over-interpreting single biomarkers. This cellular medicine approach supports more structured evaluation, clearer communication with patients, and follow-up plans that can be adjusted based on symptoms, function, and selected lab trends over time. The course is designed for clinicians, healthcare providers, and advanced learners who want a mechanism-first approach to complex gut–immune–neuroendocrine cases.

The course is delivered as two recorded days of mechanism-first teaching that builds from foundational tryptophan pathway concepts into integrated clinical reasoning. Sessions include applied discussion and Q&A to help translate the frameworks into day-to-day interpretation and monitoring decisions.

• Over 10 hours of video content
• 2 modules
• 8 lessons
• Downloadable learning guides