Mastermind 10: Post-Viral Fatigue
Immunometabolic frameworks for post-viral fatigue to guide individualized evaluation and safer therapeutic reasoning
For clinicians managing complex fatigue with clearer frameworks
This mastermind teaches a cellular medicine framework for understanding (and treating) post-viral fatigue through innate immune activation, energy regulation, and the micro- biology of inflammation resolution. Dr. Seeds presents a detailed exploration and analysis of the role of the cGAS–STING pathway and its effect on interferon and cytokine signaling, and how redox balance and mitochondrial energetics shape symptom patterns and recovery capacity. The course identifies a number of different molecules that can help address inflammation, including aspirin, zinc, peptides such as LL-37 and TA-1, as well as other supplements. Dr. Seeds also shows how specialized pro-resolving mediators (SPMs), such as lipid signals derived from omega-3 and omega-6 fats, can be used to shift the body from persistent inflammation toward resolution processes, alongside practical cautions about supplement quality and combining multiple agents. Throughout the 7 lessons, you will develop a range of lenses through which to understand and treat viral assaults, such as COVID-19 and chronic fatigue syndrome (CFS). This course is well-suited for interdisciplinary clinicians and trainees who see complex chronic or post-viral cases and want a clearer mechanistic map for discussion, monitoring, and optimal clinical decision-making.
What's Included
The course is organized as mechanism-first teaching across two days, with recurring frameworks that connect innate immune signaling, immunometabolism, and inflammation resolution. It integrates lecture-style instruction with case-based and Q&A moments to support clinical interpretation without relying on fixed protocols.
- Over 10 hours of video content
- 2 modules
- 7 lessons
- Downloadable learning guides
William Seeds
MD
For more than four decades, Dr. William A. Seeds has advanced medical science through clinical practice, research, and physician education. A board-certified Orthopaedic Surgeon in General and Sports Medicine, he served as Chief of Surgery at University Hospitals Conneaut Medical Center and Director of The Ohio Bone & Joint Institute
Highlights of Mastermind 10