Mastermind 14: The Brain Code

Mastermind 14: The Brain Code

COURSE
Mastermind
20 hrs 29 min
Mastermind 14: The Brain Code
Digital On-Demand
$995
Regular Price
$895
Pro Price
$749
Fellow Price
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Mastermind

A new framework on neurocognitive dysfunction to interpret mitochondrial and redox mechanisms for clearer clinical reasoning, to support clinical decision-making.

For clinicians working with cognitive decline and complex cases.

In this advanced-level, 32-lesson mastermind, Dr. Seeds explores the intricate cellular pathways behind a number of neurodegenerative diseases, isolating the mechanistic issues that can set off neuronal degradation. He begins by defining neurodegenerative disease as an “energy crisis” in the cellular apparatus. Through an in-depth examination of the role of microglial cells in protecting the brain; the immune crosstalk with the CNS; and the role of astrocytes, the metabolic intermediaries of the brain, Dr. Seeds offers crucial insight into the cellular roots of neurodegeneration. He also explores the often overlooked function of oligodendrocytes, which are responsible for myleination, and the importance of the gut-brain axis. Ultimately, the course arrives at the power of redox as a functional lens through which to restore brain homeostasis and potentially prevent or offset neurodegeneration and loss of cognitive function that accompanies Parkinson’s , Alzheimer’s, and Multiple Sclerosis. In addition, Dr. Seeds outlines a unique, comprehensive framework that clinicians can apply in their practice to both address neurodegenerative disease and optimize cognitive function – as well as overall patient healthspan. Through these immersive lessons, you will gain a systems-level understanding of key cellular players (neurons, microglia, astrocytes, oligodendrocytes), mitochondrial networks, redox dynamics, neuroimmune crosstalk, and clinical protocols.

What's Included

This course is organized as themed, recorded lessons that move from core mechanisms of neurocognitive dysfunction into clinician-facing frameworks for evaluation and follow-up. The structure supports stepwise learning, with repeated attention to evidence limitations and how to interpret findings over time.

  • 20h 33m total runtime
  • 8 modules
  • 32 lessons
  • Downloadable learning guides
  • Eligible for 14.00 AMA PRA Category 1 Credits™

This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the co-sponsorship of Northeast Ohio Medical University and Seeds Scientific Research and Performance Institute. Northeast Ohio Medical University is accredited by the ACCME to provide continuing education for physicians. Northeast Ohio Medical University designates this live activity and enduring material activity for a maximum of 14.00 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Highlights

Watch highlights from Mastermind 14

Mastermind 14 Highlights
Mastermind 14 Highlights

Course Curriculum

32 lessons · 20 hrs 29 min

Neurons Under Siege
Lesson 1 Energy Crisis in Neurons 53:58
Lesson 2 Redox Signaling and Neurotransmitter Imbalance 54:20
Lesson 3 Loss of Synaptic Plasticity and the CDREB-BDNF Axis 1:22:12
Lesson 4 Neuronal Bioenergetics as Therapeutic Targets 41:10
Microglia
Lesson 5 Microglia Phenotypes: Guardians or Executioners? 34:34
Lesson 6 Mitochondrial Dysfunction in Microglia 41:59
Lesson 7 Immune Cell Crosstalk in the CNS 29:45
Lesson 8 Reprogramming Microglia to Restore Homeostasis 36:40
Astrocytes
Lesson 9 Astrocytic Glutamate Clearance and Excitotoxicity 16:00
Lesson 10 Astrocyte-Neuron Lactate Shuttle (ANLS) 22:24
Lesson 11 Neurovascular Unit and BBB Maintenance 12:19
Lesson 12 Targeting Astrocyte Function in Therapy 19:49
Oligodendrocytes
Lesson 13 Oligodendrocyte Development and Myelin Maintenance 1:02:07
Lesson 14 Lipid Metabolism and Myelin Integrity 1:20:54
Lesson 15 Oligodendrocyte Mitochondria and ROS Susceptibility 45:51
Lesson 16 Clinical Restoration of Myelin Function 1:34:46
Neurogenesis
Lesson 17 Neurogenesis in the Adult Brain 35:38
Lesson 18 CREB-BDNF Axis and Memory Encoding 19:42
Lesson 19 Rewiring via Experience and Stimuli 16:28
Lesson 20 Cellular Medicine Protocols for Synaptic Restoration 40:38
Gut-Brain Axis
Lesson 21 Microbiome: Microglia Signaling Pathways 31:38
Lesson 22 Vagal Nerve and Cholinergic Reflex Loop 24:20
Lesson 23 Leaky Gut, Leaky Brain: The Barrier Connection 21:22
Lesson 24 Therapeutic Targeting of the Gut–Brain Interface 24:32
The Redox Reset
Lesson 25 Insulin Resistance in the Brain 13:02
Lesson 26 Ketones, NAD⁺, and Brain Energy Shifts 20:28
Lesson 27 Sirtuins and Epigenetic Remodeling 23:12
Lesson 28 Integrated Cellular Reprogramming Strategies 52:07
Clinical Care
Lesson 29 Clinical Phenotyping of Cognitive Decline 39:56
Lesson 30 Cellular Pathway Diagnostics and Biomarkers 1:01:41
Lesson 31 Multi-Target Protocols and Case Studies 23:21
Lesson 32 Future Technologies and Neurorestoration Frontiers 52:00

Eligible for 14.0 AMA PRA Category 1 Credits™

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME). Credit is designated as AMA PRA Category 1 Credit(s).

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