Mastermind 3: Microbiome 1.0
Host-centered microbiome fundamentals for clearer gut evaluation and better follow-up planning
For clinicians building stronger microbiome clinical reasoning
In this introductory mastermind on the microbiome, Dr. Seeds focuses on the importance of assessing the individual microbiome through a close examination of the factors that can push the lining of the colon out of balance. You’ll learn practical heuristics for dysbiosis (such as obligate versus facultative anaerobes), how short-chain fatty acids like butyrate are crucial to gut energy use and immune signaling, and how tryptophan can be routed into different metabolites with downstream effects on barrier defense pathways (including AHR to IL-22 signaling). The training also reviews core features of gut immune architecture and how inflammatory signaling can shape microbial ecology over time. Clinicians have the opportunity to develop their skills in data interpretation and application when considering the use of either medication and nutrition to influence symptoms. The cellular medicine approach to understanding the microbiome is designed to help guide individualized evaluation with longitudinal follow-up using measurable endpoints such as bowel patterns and selected stool markers and is well suited for medically trained providers and advanced learners who want mechanism-informed clinical context. The course is organized in two sections and offers 8 lessons, with over 10 hours of instructional content.
What's Included
The course is organized as Day 1 and Day 2 recordings that build from core concepts into deeper mechanisms and applied clinician Q&A. It emphasizes themes-first teaching to support structured interpretation and follow-up rather than a single prescriptive protocol.
- Over 10 hours of video content
- 2 modules
- 8 lessons
- Downloadable learning guides
William Seeds
MD
For more than four decades, Dr. William A. Seeds has advanced medical science through clinical practice, research, and physician education. A board-certified Orthopaedic Surgeon in General and Sports Medicine, he served as Chief of Surgery at University Hospitals Conneaut Medical Center and Director of The Ohio Bone & Joint Institute