Mastermind 4: Autoimmune Disease

In this mastermind intensive, Dr. Seeds offers a cellular-medicine interpretation of autoimmune disorders by examining how cells manage energy and oxidative stress, with an emphasis on redox balance (NAD/NADH and NADP/NADPH) and key signaling pathways that regulate growth, repair, and recycling (AKT, mTOR, and AMPK). You’ll connect core metabolic pathways—such as glycolysis, the pentose phosphate pathway, and lactate handling—to clinical questions about oxidative burden, nutrient sensing, and stress responses and how these patterns can trigger autoimmune conditions. The curriculum also covers autophagy (cellular recycling), one-carbon metabolism (pathways that support DNA building blocks and methylation), and circadian biology to further deepen your understanding of the intersecting factors related to autoimmune disorders. The goal of the 8 lessons is to support clinicians in building their understanding of cellular mechanisms that drive disease. You will also review the nuances in lab reports, medication combinations, including peptides, and strategies for organizing complex cases. The course is designed for clinicians and other healthcare professionals, with additional relevance for researchers and advanced students who want a structured way to apply cellular metabolism and signaling concepts to autoimmune conditions.

The course is delivered as long-form, mechanistic teaching that connects cellular pathways to practical clinical interpretation. Concepts are reinforced through applied discussions and Q&A that emphasize how to organize hypotheses and revisit them with longitudinal follow-up.

• Over 10 hours of video content
• 2 modules
• 8 lessons
• Downloadable learning guides