Mastermind 8: Cellular Senescence
Cellular senescence basics for clearer inflammation patterns and more structured patient follow-up
For clinicians managing complex aging-related presentations
In this deep dive into cellular senescence, Dr. Seeds unpacks the intricacies of immunosenescence; why senescence is both good and bad; and how understanding these cellular mechanisms offers us a robust lens through which to understand aging. Along with a guest, Patrick Bradshaw, PhD, Dr. Seeds explains how senescent cells develop and, if unchecked, can create numerous negative downstream effects. When cells stop dividing yet remain biologically active, they can contribute to chronic inflammatory signaling and create havoc, affecting mitochondrial energy stress, nutrient sensing, and changes in immune surveillance, including the brain-gut–immune interface. Further, the course delves into the epigenetic influences on senescent processes. The 6 lessons also review what senescence markers and pathways can and cannot tell you, and why tissue context matters when discussing senolytics or senomodulators as therapeutic levers. Throughout the course there is an emphasis on tracking senescence to optimize therapeutic protocols.
What's Included
The course is organized as a stepwise progression from core mechanisms of senescence to integrative clinical interpretation and monitoring concepts. It revisits key ideas across sessions to reinforce an upstream-to-downstream model you can use for longitudinal follow-up and reassessment.
- Over 5 hours of video content
- 2 modules
- 6 lessons
- Downloadable learning guides
William Seeds, MD
For more than four decades, Dr. William A. Seeds has advanced medical science through clinical practice, research, and physician education. A board-certified Orthopaedic Surgeon in General and Sports Medicine, he served as Chief of Surgery at University Hospitals Conneaut Medical Center and Director of The Ohio Bone & Joint Institute before founding the Seeds Scientific Research & Performance (SSRP) Institute. He is also Founder and Medical Director of the Redox Medical Group in Beverly Hills and the bestselling author of Peptide Protocols, The Redox Promise, and The Quantum Power of GLP-1 Peptides. His contributions to sports medicine have been recognized at the NFL Hall of Fame, and he has consulted for athletes across the NFL, NHL, MLB, NBA, and Dancing with the Stars.
Highlights of Mastermind 8
Course Curriculum
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