by William Seeds, MD | Mar 25, 2026 | Article
The Father of Ketones and the Value of Exogenous Ketone Esters I’ve talked about ketones and ketone esters for many years, and I’ve now come to a place where I really have to take a more direct stand on how they’ve been marketed to the wider public,...
by William Seeds, MD | Feb 26, 2026 | Article
Recently I presented a Rabbit Hole (1/19/2026) related to the polyamine, spermidine, in response to a 2025 article, “Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis,” which appeared in Nature Cell Biology. I was...
by William Seeds, MD | Jan 20, 2026 | Article
Microglia are the brain’s resident immune cells — but they’re much more than just defenders. Think of them as a combination of janitors, gardeners, and neighborhood watch patrols that keep the brain healthy, balanced, and adaptable. The Brain’s First Responders...
by William Seeds, MD | Dec 17, 2025 | Article
Introduction Understanding brain metabolism offers insight not only into the potential root causes of neurodegenerative disease but also the interventions that can positively impact cognitive functioning. In particular, looking at the pathways, energy use, and factors...
by William Seeds, MD | Nov 12, 2025 | Article
This is a further dive into and expansion of a Journal Club video that I offered in September 2025 in response to a fascinating article related to the power of GLP-1 peptides to create positive epigenetic changes at the cellular level. The study, Semaglutide...
